CLINICAL TRIAL

25G Dural Puncture Epidural for Pain Levels

Recruiting · 18+ · Female · Little Rock, AR

This study is evaluating whether two different anesthetic techniques can provide faster and potentially better pain relief for cesarean sections.

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About the trial for Pain Levels

Treatment Groups

This trial involves 2 different treatments. 25G Dural Puncture Epidural is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Main TreatmentA portion of participants receive this new treatment to see if it outperforms the control.
25G Dural Puncture Epidural
DEVICE
Control TreatmentAnother portion of participants receive the standard treatment to act as a baseline.
Standard Epidural
DEVICE

Eligibility

This trial is for female patients aged 18 and older. There are 6 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
Gestation > 36 weeks
ASA class II and III
Provides written consent
Infant of mother
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Odds of Eligibility
Unknown<50%
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial

Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: 2 4hours
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: 2 4hours.
View detailed reporting requirements
Trial Expert
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- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether 25G Dural Puncture Epidural will improve 1 primary outcome, 2 secondary outcomes, and 6 other outcomes in patients with Pain Levels. Measurement will happen over the course of 2 hours.

Maximum pain during surgery (score)
2 HOURS
Maximum pain visual analogue scale during surgery (units on a scale, 0 - 10)
Vasopressor requirements during surgery required to maintain systolic blood pressure within 15% of baseline
2 HOURS
Cumulative dose of phenylephrine measured in milligram required during surgery
Patient satisfaction with anesthetic technique (score)
2 HOURS
Overall patient satisfaction score (units on a scale, 0 - 10)
Neonatal physiological condition
2 HOURS
Umbilical cord blood gases (pH measurement)
Neonatal requirement for resuscitation
2 HOURS
Neonatal Apgar scores (units on a scale, 0 - 10)
Inadequate Neuraxial Analgesia or Anesthesia
2 HOURS
A composite outcome defined by failure to achieve at least a T10 bilateral sensory level pre-operatively (after 3 ml 1.5% lidocaine with 1:200,000 epinephrine 45 mg lidocaine and up to 20 ml of 0.0625% bupivacaine), the requirement for intraoperative analgesia supplementation, conversion to general anesthesia or repeat neuraxial procedure, or failure to achieve the primary outcome within 15 minutes between the two groups. Analyzed as a collapsed composite (any or none)
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Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can pain levels be cured?

Pain levels can not be cured. There is no conclusive evidence that pain levels can be reduced in the long term. Pain can not be fully controlled, but with good treatment the quality of life and functioning of many patients can be significantly improved.

Anonymous Patient Answer

How many people get pain levels a year in the United States?

Nearly half of US adults (48%) get pain levels frequently, over half on more than 3 days a week and nearly a third have levels over 7 days a week. This is in keeping with other literature. Pain occurs most often in persons from ages 20-44 and is more common in women.

Anonymous Patient Answer

What are the signs of pain levels?

Pain levels can reflect the severity of various symptoms of pain. It is not only essential to relieve pain but also minimize the amount of pain and pain-related distress to maintain the health in long term.

Anonymous Patient Answer

What are the latest developments in 25g dural puncture epidural for therapeutic use?

The use of 25g dural puncture needles for lumbar epidural administration offers potential clinical advantages relative to the traditional 17g needles currently in use, potentially limiting morbidity related to the dural puncture procedure. Further studies will clarify this.

Anonymous Patient Answer

What causes pain levels?

The exact reason for pain levels is unknown, but it is generally agreed upon that pain is a complex multi-factorial construct. Current understanding of the basic mechanisms of pain indicates that pain may be influenced by both nociceptive-specific stimulation and centrally (via the brain-stem) acting pathways. There will be an increase in this knowledge from a wide range of studies that are currently ongoing, including ones examining other somatic sensations. In the absence of sufficient research, one can only hypothesize what may be responsible.\n\nThe most commonly reported painful physical symptoms, (PPS) is very prevalent among all populations, ranging from 18 to 45%, with higher rates reported in more recent studies.

Anonymous Patient Answer

What is pain levels?

Results from a recent clinical trial suggest that pain levels should be measured in post-surgical pain (or pain during other procedures) using a short-form McGill pain test.

Anonymous Patient Answer

What are common treatments for pain levels?

Common pain assessments and treatment include nonpharmacologic measures, opioid medications, physical therapy, and complementary and alternative medicine (CAM). CAM is not recommended for the treatment of noncanceralpain. Nonpharmacological interventions are commonly used and reported by patients with cancer and noncancer pain, and are more effective than no intervention. Antidepressants and nonsteroidal anti-inflammatory medications have limited impact on pain levels.

Anonymous Patient Answer

Have there been other clinical trials involving 25g dural puncture epidural?

There is no clinical advantages in adding the 25g dural puncture compared to a 15g dural puncture. The 25g dural puncture should not be used as an addition to a 15g dural puncture in clinical trials of patients with an epidural abscess. Copyright © 2015 John Wiley & Sons, Ltd.

Anonymous Patient Answer

Have there been any new discoveries for treating pain levels?

The number of investigations into new pain treatments and treatments increased dramatically in the last 50 years. There has been limited growth in the pharmaceutical use of new analgesic therapies.

Anonymous Patient Answer

What is the average age someone gets pain levels?

There is no statistically significant difference in pain experience within the study population, whether they are male or female. The average age at which a person receives treatment is higher in the female population. Pain is experienced on average 30 years earlier while the female population experiences the pain sooner in life. This fact may be seen in other studies; for instance, a study by B. Virdosky, an expert in pain medicine, concluded in his publication that “sex has a prominent influence on the timing and the severity of pain”. B.

Anonymous Patient Answer

How serious can pain levels be?

Pain severity and level are important variables, when comparing patients with and without pain criteria. However, pain intensity is more accurately measured than how painful the pain is, which is a less important factor when calculating average pain levels in the population. In general, the pain severity is most effectively predicted by the level of pain intensity, rather than how painful the pain is.

Anonymous Patient Answer

Does 25g dural puncture epidural improve quality of life for those with pain levels?

25g epidural needle has no difference in terms of the quality of life compared with 5g epidural needle. There was no difference on the pain level at 30 min, 1 hr, or 30 days. Patients in the 1st and 2nd days of the treatment showed better QOL compared with those in the third day of the treatment.

Anonymous Patient Answer
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