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CHASE Trial Summary
This trial will test if a new drug is safe and effective for people with a certain skin condition.
CHASE Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.CHASE Trial Design
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Who is running the clinical trial?
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- I will be taking doxycycline.I haven't had eye surgery in the last 90 days.I have a sore on my cornea.I do not have any active eye infections or diseases that could affect my vision.I have severe damage to the stem cells in the front part of my eye.I have not had Botox injections for eyelid drooping in the last 90 days.More than 75% of the edge of my cornea in one eye has reduced blood flow.I have severe eyelid inflammation or severe gland issues in my eyelids.I have had surgery for my condition before.I am not willing to stop wearing contact lenses in the eye being studied.I have had persistent corneal epithelial defects for over a week due to an eye condition.I haven't used chemotherapy drugs in the last 7 days and don't plan to use them during the study.I have not used Oxervate in my study eye in the last 30 days.I have severe burns on the cornea of my study eye.My eyelid has severe issues contributing to my persistent eye condition.
- Group 1: Cohort 2, Arm 3
- Group 2: Cohort 2, Arm 1
- Group 3: Cohort 2, Arm 2
- Group 4: Cohort 1, Arm 1
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is the first cohort and arm of this experiment recognized by the FDA?
"Cohort 1, Arm 1 was awarded a safety score of 2 since it is in Phase 2; this suggests that the data collected thus far supports the drug's security but does not yet demonstrate effectiveness."
How many healthcare facilities have been approved to participate in this experiment?
"As of right now, recruitment is underway at 5 medical sites. These locations are in Saint Louis, Chesterfield and Kansas City as well as 2 additional places. Prospective participants should opt for the nearest site to lessen any travel-related inconveniences associated with taking part in this trial."
Are there any open slots in this investigation to enroll volunteers?
"Affirmative, the information hosted on clinicaltrials.gov indicates that this investigation is actively seeking participants. It was first published on February 1st 2023 and has since been updated to its present form as of 2/6/2023. The study requires two individuals from five distinct sites for enrollment."
Approximately how many participants are involved in this clinical trial?
"Affirmative. Per the data located on clinicaltrials.gov, this medical trial is actively seeking participants. It was initially posted to the website in February of 2023 with recent updates occuring 6 days later. A total of 2 patients must be recruited from 5 individual sites for successful completion of the study."
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