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CAM treatments for Multiple Sclerosis

Phase 2
Waitlist Available
Led By Victor W Mark, MD
Research Sponsored by National Multiple Sclerosis Society
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up before treatment, and immediately, 6 months, and 12 months after the end of treatment.
Awards & highlights

Study Summary

This study will compare two different kinds of physical therapy to improve use of the hands in individuals with multiple sclerosis (MS). One treatment will be Constraint-Induced Movement therapy (CI therapy), the other will be a set of Complementary and Alternative Medicine (CAM) treatments (yoga, relaxation exercises, aquatherapy, massage). The study will determine which of the two forms of treatment is more successful for improving hand use.

Eligible Conditions
  • Multiple Sclerosis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~before treatment, and immediately, 6 months, and 12 months after the end of treatment.
This trial's timeline: 3 weeks for screening, Varies for treatment, and before treatment, and immediately, 6 months, and 12 months after the end of treatment. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Motor Activity Log (MAL)
Secondary outcome measures
Baecke Activity Questionnaire
EDSS (Expanded Disability Status Scale)
Fatigue Severity Scale (FSS)
+5 more

Trial Design

2Treatment groups
Active Control
Group I: CAM treatmentsActive Control1 Intervention
CAM treatments are holistic physical treatments designed to work on the entire body to improve quality of life and overall health. This study will use yoga, relaxation exercises, aquatherapy (pool therapy), and massage.
Group II: CI TherapyActive Control1 Intervention
CI therapy involves repetitive practice with the more-affected hand on typical daily living activities (such as stacking objects, pouring, moving objects) for 3.5 hours per day, along with physical restraint of the better hand to keep it from assisting, and home practice exercises.

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Who is running the clinical trial?

National Multiple Sclerosis SocietyLead Sponsor
96 Previous Clinical Trials
9,439 Total Patients Enrolled
94 Trials studying Multiple Sclerosis
9,085 Patients Enrolled for Multiple Sclerosis
Victor W Mark, MDPrincipal InvestigatorUniversity of Alabama at Birmingham
1 Previous Clinical Trials
7 Total Patients Enrolled
1 Trials studying Multiple Sclerosis
7 Patients Enrolled for Multiple Sclerosis

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Improving Hand Use in Multiple Sclerosis
Victor W. Mark 2010. "Improving Hand Use in Multiple Sclerosis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01081275.
All > Primary Progressive Multiple Sclerosis
~4 spots leftby May 2025
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