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Loncastuximab Tesirine for Follicular Lymphoma (LOTIS-6 Trial)
LOTIS-6 Trial Summary
This trial will compare the effectiveness of loncastuximab tesirine to idelalisib in people with follicular lymphoma that has returned or does not respond to treatment.
- Follicular Lymphoma
LOTIS-6 Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.LOTIS-6 Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
Could you elaborate on the other investigations that have been conducted regarding Loncastuximab Tesirine?
"Currently, there are 18 ongoing research projects using Loncastuximab Tesirine with 3 of them in their final Phase. The majority of the trials take place in Cleveland, Ohio yet 581 different places have registered for various studies involving Loncastuximab Tesirine."
For what ailments is Loncastuximab Tesirine frequently recommended?
"Loncastuximab Tesirine is a potent medication for chronic lymphocytic leukemia and it can also be employed to combat relapsed large b-cell lymphoma, multiple lines of systemic treatment, as well as other forms of non-Hodgkin's B-Cell Lymphomas."
To what degree can the utilization of Loncastuximab Tesirine be detrimental to patients?
"Leveraging our internal evaluation criteria, Power assigned a score of 2 to Loncastuximab Tesirine's safety due to the fact that this is only a Phase 2 trial and has yet to demonstrate efficacy."
Is this project actively seeking participants?
"Data hosted on clinicaltrials.gov elucidates that this trial is not presently enlisting volunteers. This research project, which was initially published on November 4th 2021, has most recently been adjusted on July 26th 2022; however, 1737 alternative trials are currently enrolling patients."
What is the estimated enrolment for this clinical trial?
"This research study is no longer accepting any new participants. It was created on November 4th 2021 and last modified on July 26th 2022. For those seeking other clinical trials, there are currently 1719 studies recruiting for refractory follicular lymphoma and 18 trials involving Loncastuximab Tesirine actively enrolling patients."
Does this experiment represent a pioneering approach to research?
"Since 2014, Loncastuximab Tesirine has been under investigation. The initial test was sponsored by Gilead Sciences and included 50 participants. After the Phase 1 trial success of this drug in 2014, it received its Phase 2 approval. Nowadays there are 18 concurrent trials for Loncastuximab Tesirine taking place in 176 cities over 31 countries worldwide."
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