Radiation Therapy

Treatment (AI-directed analysis, SBRT) for Lung Cancer

N/A

Waitlist Available

Led By Mohamed E Abazeed, MD, PhD

Research Sponsored by Northwestern University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Must not have

Be younger than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Upup to 5 years

Awards & highlights

No Placebo-Only Group

Study Summary

This trial tests AI to help improve dose prescription for lung radiation therapy to help reduce local recurrence.

Eligible Conditions

Lung Cancer
Non-Small Cell Lung Cancer

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 5 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 5 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

LFS

Local failure free survival (LFS)

Secondary outcome measures

Adherence of the prescribing physician to the dose recommended

Incidence of adverse events

Progression-free survival (PFS)

+1 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Treatment (AI-directed analysis, SBRT)Experimental Treatment7 Interventions

Patients undergo radiation planning with AI-directed analysis for dose recommendations with Deep Profiler + iGray software on study. Patients then undergo SBRT on study. Patients also undergo PET, CT, MRI, and/or x-ray imaging during screening and follow-up.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Positron Emission Tomography

2008

Completed Phase 2

~2240

Stereotactic Body Radiation Therapy

2019

Completed Phase 2

~770

Computed Tomography

2017

Completed Phase 2

~2890

Magnetic Resonance Imaging

2017

Completed Phase 3

~1250

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Find a site

Who is running the clinical trial?

Northwestern UniversityLead Sponsor

1,529 Previous Clinical Trials

913,291 Total Patients Enrolled

National Cancer Institute (NCI)NIH

13,412 Previous Clinical Trials

41,238,996 Total Patients Enrolled

Varian Medical SystemsIndustry Sponsor

52 Previous Clinical Trials

3,551 Total Patients Enrolled

Mohamed E Abazeed, MD, PhDPrincipal Investigator

Northwestern University

Media Library

Stereotactic Body Radiation Therapy (Radiation Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT05802186 — N/A

Lung Cancer Research Study Groups: Treatment (AI-directed analysis, SBRT)

Lung Cancer Clinical Trial 2023: Stereotactic Body Radiation Therapy Highlights & Side Effects. Trial Name: NCT05802186 — N/A

Stereotactic Body Radiation Therapy (Radiation Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05802186 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still vacancies for volunteers to join this trial?

"As reported on clinicaltrials.gov, the recruitment for this study has ended as of March 24th 2023. Initially posted on May 31st 2023, this trial is no longer searching for participants; however, there are 6463 other trials that require patients at present time."

Answered by AI

What is the fundamental purpose of this clinical experiment?

"Over a duration of two years, the research team will evaluate this study's primary objective of Overall Survival. Secondary metrics include evaluating Respiratory Function via RTOG Pulmonary Function Test Toxicity Scale, Incidence of Adverse Events through National Cancer Institute-Common Terminology Criteria for Adverse Events v5.0., and assessing physician adherence to prescribed doses as recommended by Deep Profiler +iGray software over one to two weeks during SBRT treatment."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Stereotactic Body Radiation Therapy Planning With Artificial Intelligence-Directed Dose Recommendation for Treatment of Primary or Metastatic Lung Tumors, RAD-AI Study

2023. "Stereotactic Body Radiation Therapy Planning With Artificial Intelligence-Directed Dose Recommendation for Treatment of Primary or Metastatic Lung Tumors, RAD-AI Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05802186.