← Back to Search

Bone Graft

Bone Graft Materials for Wound Healing After Tooth Extraction

N/A
Recruiting
Led By Angela Palaiologou-Gallis, DDS
Research Sponsored by The University of Texas Health Science Center at San Antonio
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Have a dehiscence of the buccal or lingual bony plate of the tooth socket extending no more than 50% of the total depth of the socket.
Have at least 10mm of alveolar bone height, without impinging on the maxillary sinus or inferior alveolar canal.
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline to 18-20 weeks
Awards & highlights

Study Summary

This trial is testing different combinations of bone graft materials to see which results in the best growth of new bone 18-20 weeks after the surgery.

Who is the study for?
This trial is for non-pregnant women, including those post-hysterectomy, tubal ligation, or menopause. Participants should be nonsmokers or light smokers (less than 10 cigarettes per day), have a tooth excluding molars needing extraction with enough bone height and space for an implant. Those with active infections other than periodontitis, heavy smokers, certain medical conditions affecting healing, or on specific medications are excluded.Check my eligibility
What is being tested?
The study aims to compare the effectiveness of different graft materials in dental ridge preservation after tooth extraction. It will measure new bone formation using DFDBA fibers alone versus particulate form and combinations with xenograft material over approximately 18-20 weeks.See study design
What are the potential side effects?
While not explicitly stated in the provided information, potential side effects may include discomfort at the site of surgery, swelling, bruising, infection risk at the graft site and delayed wound healing.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
My tooth socket's bone wall is partially broken but not more than half.
Select...
I have enough jawbone height for dental implants without affecting my sinus or nerve canal.
Select...
I need one tooth (not a molar) removed as advised by a dentist.
Select...
I am scheduled to get a dental implant for my missing tooth.
Select...
I have enough jawbone height for dental implants without affecting my sinus or nerve canal.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline to 18-20 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 18-20 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Percentage vital bone formation
Secondary outcome measures
Change in buccal ridge height
Change in lingual ridge height
Change in ridge width
+2 more

Trial Design

4Treatment groups
Active Control
Group I: Group 3 Vallos-FActive Control1 Intervention
Subjects will be randomized into one of the four groups and receive the corresponding material for ridge preservation following tooth extraction.
Group II: Group 1 VallosActive Control1 Intervention
Subjects will be randomized into one of the four groups and receive the corresponding material for ridge preservation following tooth extraction.
Group III: Group 2 VallomixActive Control1 Intervention
Subjects will be randomized into one of the four groups and receive the corresponding material for ridge preservation following tooth extraction.
Group IV: Group 4 Vallomix-FActive Control1 Intervention
Subjects will be randomized into one of the four groups and receive the corresponding material for ridge preservation following tooth extraction.

Find a Location

Who is running the clinical trial?

The University of Texas Health Science Center at San AntonioLead Sponsor
452 Previous Clinical Trials
91,294 Total Patients Enrolled
Angela Palaiologou-Gallis, DDSPrincipal InvestigatorUniversity of Texas Health Science Center San Antonio
Brian Mealey, DDS, MSPrincipal InvestigatorUniversity of Texas Health Science Center San Antonio
1 Previous Clinical Trials
74 Total Patients Enrolled

Media Library

Ridge Preservation (Bone Graft) Clinical Trial Eligibility Overview. Trial Name: NCT05400213 — N/A
Wound Healing Research Study Groups: Group 3 Vallos-F, Group 1 Vallos, Group 2 Vallomix, Group 4 Vallomix-F
Wound Healing Clinical Trial 2023: Ridge Preservation Highlights & Side Effects. Trial Name: NCT05400213 — N/A
Ridge Preservation (Bone Graft) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05400213 — N/A
Wound Healing Patient Testimony for trial: Trial Name: NCT05400213 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it still possible to join this clinical investigation?

"Affirmative. Clinicaltrials.gov lists this clinical trial as actively recruiting participants, having been posted on August 2nd 2022 and last updated the same day. 120 patients are required from a single medical facility."

Answered by AI

What is the cap for enrollment in this clinical trial?

"Affirmative, the information published on clinicaltrials.gov affirms that this medical trial is recruiting patients. Initially posted on August 2nd 2022 and last edited on the same date, 120 participants are required at a single research centre."

Answered by AI

Who else is applying?

What state do they live in?
Texas
Nevada
How old are they?
18 - 65
What site did they apply to?
University of Texas Health Science Center at San Antonio (Dental School)
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
0
3+

Why did patients apply to this trial?

I have needed a couple teeth extracted and am unable yet financially to get implants.
PatientReceived 2+ prior treatments
Recent research and studies
clinicaltrials.govStudy
Wound Healing Following Tooth Extraction and Ridge Preservation Using DFDBA Alone in Particulate Fiber Form and in Combination With Xenograft
2022. "Wound Healing Following Tooth Extraction and Ridge Preservation Using DFDBA Alone in Particulate Fiber Form and in Combination With Xenograft". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05400213.
~43 spots leftby Mar 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top