Group 3 for Wound Healing

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Texas Health Science Center at San Antonio (Dental School), San Antonio, TX
Wound Healing+2 More
Vallos-F - Device
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

The primary aim of the study is to determine the amount of newly formed vital bone, residual graft material, and "connective tissue/other" 18 to 20 weeks after ridge preservation is performed using DFDBA fibers alone, DFDBA particulate alone, a combination of xenograft and DFDBA particulate, or a combination of xenograft and DFDBA fibers.

Eligible Conditions

  • Wound Healing
  • Dental Extraction

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 5 Secondary · Reporting Duration: Baseline to 18-20 weeks

Baseline to 18-20 weeks
Change in buccal ridge height
Change in lingual ridge height
Change in ridge width
Week 20
Percentage of connective tissue
Percentage of residual graft material
Percentage vital bone formation

Trial Safety

Trial Design

8 Treatment Groups

Group 3
1 of 8
Group 4
1 of 8
Group 2
1 of 8
Group 1
1 of 8
Group 4 Vallomix-F
1 of 8
Group 2 Vallomix
1 of 8
Group 3 Vallos-F
1 of 8
Group 1 Vallos
1 of 8
Active Control

120 Total Participants · 8 Treatment Groups

Primary Treatment: Group 3 · No Placebo Group · N/A

Group 3
Device
ActiveComparator Group · 1 Intervention: Vallos-F · Intervention Types: Device
Group 4
Device
ActiveComparator Group · 1 Intervention: Vallomix-F · Intervention Types: Device
Group 2
Device
ActiveComparator Group · 1 Intervention: Vallomix · Intervention Types: Device
Group 1
Device
ActiveComparator Group · 1 Intervention: Vallos · Intervention Types: Device
Group 4 Vallomix-F
Device
ActiveComparator Group · 1 Intervention: Vallomix-F · Intervention Types: Device
Group 2 Vallomix
Device
ActiveComparator Group · 1 Intervention: Vallomix · Intervention Types: Device
Group 3 Vallos-F
Device
ActiveComparator Group · 1 Intervention: Vallos-F · Intervention Types: Device
Group 1 Vallos
Device
ActiveComparator Group · 1 Intervention: Vallos · Intervention Types: Device

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline to 18-20 weeks
Closest Location: University of Texas Health Science Center at San Antonio (Dental School) · San Antonio, TX
Photo of San Antonio  1Photo of San Antonio  2Photo of San Antonio  3
2013First Recorded Clinical Trial
1 TrialsResearching Wound Healing
1 CompletedClinical Trials

Eligibility Criteria

Age 18+ · All Participants · 7 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
One tooth, excluding molars, that has been identified by dental faculty as requiring a single tooth extraction.
A dental implant is indicated and treatment planned to replace the missing tooth.
You have adequate restorative space for a dental implant-retained restoration.
You have a dehiscence of the buccal or lingual bony plate of the tooth socket extending no more than 50% of the total depth of the socket.
You are female and of child-bearing potential.
You are a current smoker or a former smoker.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.