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Docetaxel vs Paclitaxel for Breast Cancer
Study Summary
This trial looks at two different drugs to see how well they reduce chemotherapy-induced nerve damage in African American patients with early to mid-stage breast cancer.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have not been treated with taxane or platinum-based drugs.Your liver enzymes (AST and ALT) and alkaline phosphatase levels must not be too high.I am a woman diagnosed with stage I-III breast cancer within the last 84 days.I am planning to receive specific chemotherapy before or after surgery.Your total bilirubin level should not be higher than the normal limit.I do not have nerve damage in my hands or feet.Women who could become pregnant must have a test to check if they are pregnant within 2 weeks before joining the study.I am fully active or can carry out light work.I have had cancer before but haven't been treated with taxane, platinum, or vinca alkaloids.I am using or will use effective birth control or abstain from sex during the study.I am willing and able to agree to the study's procedures.
- Group 1: Arm A (paclitaxel)
- Group 2: Arm B (docetaxel)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Have other research projects employed Docetaxel as a component?
"Currently, 1088 trials investigating the efficacy of Docetaxel are in progress. Of those active studies, 317 have reached Phase 3 status. Although Shanghai is by far the most popular area for these trails to be conducted (58781 locations), other areas worldwide have launched investigations as well."
To what degree does Docetaxel pose a risk to patients?
"Considering the Phase 2 status of Docetaxel, there is sufficient clinical data to validate its safety but none to demonstrate efficacy; thus it was assigned a score of 2."
What maladies is Docetaxel employed to remedy?
"Docetaxel is the go-to option for neoplasm metastasis, and can also be beneficial in treating a variety of other medical conditions such as soft tissue sarcoma (STS), locally advanced non-small cell lung cancer, or even metastatic bladder cancer."
How many participants are being included in this clinical trial?
"This medical trial has closed its recruitment window. The study was initially listed on June 27th, 2019 and the last update occurred April 14th, 2022. Currently, there are 2432 studies recruiting participants with breast conditions and 1088 trials accepting volunteers for Docetaxel research."
Is the enrollment process for this study still open?
"The data found on clinicaltrials.gov displays that this medical trial is not open for enrollment any longer, as the last update was in April of 2022 and it first began recruiting patients back in June 2019. While recruitment has ceased, there are still 3520 other trials searching for volunteers across the globe."
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