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Procedure

Endolumenal Partial Myotomy for Achalasia

Phase 2

Waitlist Available

Research Sponsored by The Oregon Clinic

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Ability to undergo general anesthesia

Candidate for elective Heller myotomy

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

Study Summary

This trial is testing a new, less invasive treatment for achalasia, a condition where the lower esophageal sphincter fails to relax.

Who is the study for?

This trial is for individuals who have trouble swallowing due to a condition called esophageal achalasia. Participants must be able to consent, undergo anesthesia, and be candidates for a type of surgery known as Heller myotomy. Those with past chest or esophagus surgeries or conditions that make upper GI endoscopy risky can't join.Check my eligibility

What is being tested?

The study is testing a new procedure called flexible endoscopic myotomy which aims to treat achalasia without the need for more invasive surgery. It involves cutting muscles at the lower end of the esophagus through an internal approach using an endoscope.See study design

What are the potential side effects?

Potential side effects may include discomfort, bleeding, infection risk from the procedure, and possible complications related to general anesthesia.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I can safely be put under general anesthesia.

Select...

I am a candidate for surgery to treat swallowing difficulties.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Esophageal function testing

Secondary outcome measures

Quality of life score

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

The Oregon ClinicLead Sponsor

13 Previous Clinical Trials

1,470 Total Patients Enrolled

1 Trials studying Achalasia

350 Patients Enrolled for Achalasia

Media Library

Endolumenal Partial Myotomy (Procedure) Clinical Trial Eligibility Overview. Trial Name: NCT01302288 — Phase 2

Achalasia Clinical Trial 2023: Endolumenal Partial Myotomy Highlights & Side Effects. Trial Name: NCT01302288 — Phase 2

Endolumenal Partial Myotomy (Procedure) 2023 Treatment Timeline for Medical Study. Trial Name: NCT01302288 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

To what extent could this treatment be detrimental to patients' health?

"According to the internal assessment at Power, this therapy registers a safety rating of 2 since it is in the Phase 2 trial stage. This implies that some data affirms its security but there is not yet any evidence verifying its efficacy."

Answered by AI

Is enrollment available for this clinical investigation?

"The current recruitment is in search of 20 achalasia patients, aged between 18 and 85. Additional conditions they must meet are: being a suitable candidate for elective Heller myotomy, ability to tolerate general anesthesia and capacity to provide informed consent."

Answered by AI

Can people below the age of 50 participate in this experiment?

"To be eligible for this trial, applicants must have aged between 18 and 85. For individuals who are younger than eighteen or older than 65, there is a total of 17 different clinical trials available to investigate their particular medical condition."

Answered by AI

Are there still slots available for participants in this research program?

"According to clinicaltrials.gov, this particular trial is no longer actively recruiting participants; its initial posting was October 1st 2010 and last updated February 25th 2011. Nonetheless, there are 17 other medical trials that presently have space for new patients."

Answered by AI

Recent research and studies

EndoscopyJournal

Peroral Endoscopic Myotomy (POEM) for Esophageal Achalasia

Inoue, H., H. Minami, Y. Kobayashi, Y. Sato, M. Kaga, M. Suzuki, H. Satodate, N. Odaka, H. Itoh, and S. Kudo. 2010. “Peroral Endoscopic Myotomy (POEM) for Esophageal Achalasia”. Endoscopy. Georg Thieme Verlag KG. doi:10.1055/s-0029-1244080.

EndoscopyJournal

Peroral Endoscopic Myotomy (POEM) for Esophageal Achalasia

clinicaltrials.govStudy

Endolumenal Partial Myotomy for the Treatment of Esophageal Achalasia

2010. "Endolumenal Partial Myotomy for the Treatment of Esophageal Achalasia". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01302288.

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