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Onapristone for Breast Cancer
Study Summary
This trial is testing a new drug to see if it works well with another existing drug to treat metastatic breast cancer.
- Breast Cancer
- Cancer
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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- I'm sorry, but you did not provide any specific conditions in your question. Could you please provide me with the list of conditions that need to be summarized?You have a serious illness or disease that is significant enough to be noticed by your doctor.You can still participate in the study if you have already received other standard treatments for your condition, like mTOR inhibitors.You have already taken oral medications called cyclin-dependent kinase (CDK)4/6 inhibitors for the treatment of metastatic cancer.You have already received CDK4/6 inhibitors as part of your previous treatment plan.You have or had cancer that has spread to your brain or spinal cord and is causing symptoms.You have a heart condition called long QT syndrome, or someone in your family has had unexplained sudden death or was born with long QT syndrome.You have been treated with a medication that blocks the effects of progesterone in the past.You have already received fulvestrant as a treatment for metastatic cancer.You have severe heart failure symptoms that significantly limit your daily activities.
- Group 1: Onapristone In Combination with Fulvestrant
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is this medical trial actively seeking participants?
"Clinicaltrials.gov's records indicate that this clinical trial is currently in search of candidates, after having been published on October 5th 2021 and last revised on July 7th 2022."
What medicinal purposes does Onapristone typically serve?
"Endocrine therapy, breast cancer, and certain diseases can all be managed using onapristone."
What other empirical research has been conducted using Onapristone?
"Presently, there are 136 active clinical trials surveying the impacts of Onapristone with 32 studies in their final stage. While some trails for this drug may be found in Shanghai, a total of 5812 locations across the world have opened up opportunities to participate in these research projects."
How many individuals are actively involved in this research trial?
"Affirmative. Information posted on clinicaltrials.gov reveals that this research project is in the process of recruiting patients, initially published on October 5th 2021 and most recently updated July 7th 2022. A total of 39 participants are needed from 2 medical centres."
Has Onapristone been granted authorization by the FDA?
"Considering the Phase 2 status of this trial, our team at Power assigned Onapristone a score of 2 for safety. This indicates that there is evidence supporting its security but no clinical data has been provided in regards to efficacy."
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