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Study Summary
This trial will compare the safety and effectiveness of ATS907 to latanoprost, a similar medication, in people with glaucoma or ocular hypertension.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2015 Phase 4 trial • 157 Patients • NCT02003391Trial Design
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- My eye pressure was high during my last two check-ups in the morning and one in the afternoon.My eye pressure is below 32 mm Hg without medication after a washout period.My eye pressure was high during my last two check-ups.My eye pressure is below 36 mm Hg without medication after a washout period.I have had vision correction surgery in the eye being studied.I have not had cataract or any eye surgery in the last 3 months.I haven't had any major eye infections or inflammation in the last 3 months.I have a serious eye condition that affects the cornea's shape or clarity.I am not pregnant, nursing, or planning to become pregnant and use birth control.I have been diagnosed with glaucoma or high eye pressure in both eyes.I am willing to stop all eye pressure medications for the study.You have important problems in your blood tests when you were checked before the study.I haven't changed my medication that could affect my eye pressure or blood pressure in the last week.I have had glaucoma surgery or laser treatment in my study eye.You can see clearly with each eye at least as well as 20/200.I have a history of specific types of glaucoma in one or both eyes.I am 18 years old or older.I do not have any uncontrolled major illnesses like diabetes or heart disease.The thickness of your cornea in the eye being studied is below 480 or above 600 micrometers.I do not have serious eye conditions that could worsen during the study.
- Group 1: Stage 1 - Arm 4 - Dose 4
- Group 2: Stage 1 - Arm 2 - Dose 2
- Group 3: Stage 2 - Arm 2 - Dose B - to be selected based on Stage 1
- Group 4: Stage 1 - Arm 1 - Dose 1
- Group 5: Stage 2 - Arm 1 - Dose A - to be selected based on Stage 1
- Group 6: Stage 2 - Arm 3 -Timoptic 0.5% BID
- Group 7: Stage 1 - Arm 3 - Dose 3
- Group 8: Stage 1 - Arm 5 - Vehicle
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
In what geographical areas is this research trial being conducted?
"The current trial is in full swing at 5 different facilities, 3 of which are located in Cleveland, St. Joseph and San Antonio with the remaining two elsewhere. For convenience's sake, it may be beneficial to select a location closest to you if enrolling."
What is the participant capacity of this research endeavor?
"Unfortunately, this research protocol is no longer accepting patient enrolment. The trial was introduced on January 1st 2012 and the latest changes were made October 30th 2012. Nevertheless, there are currently 940 studies for glaucoma in various stages of recruitment as well as 8 trials specifically examining ATS907 – Dose 2 that participants can sign up to join."
What experiments have been conducted in association with Stage 1 - ATS907 - Dose 2 thus far?
"At the moment, 8 active clinical trials are assessing Stage 1 - ATS907 - Dose 2 with 4 of them in their concluding Phase 3. Of these ongoing studies for Stage 1 - ATS907 - Dose 2, many are situated in Campinas, São Paulo and distributed across 14 different sites."
Is enrollment open for this trial at the moment?
"This medical trial is currently not accepting prospective participants. It was first published on January 1st 2012, with its last revision being made October 30th 2012. For those exploring other studies, 940 trials are actively looking for glaucoma suspects and 8 clinical studies have Stage 1 - ATS907 - Dose 2 open enrollment at the present moment."
To what illnesses does Stage 1 - ATS907 - Dose 2 typically provide relief?
"ATS907 - Dose 2 from Stage 1 is regularly prescribed for individuals who did not respond to treatment with beta-blockers. Additionally, it may be used as an adjunctive or replacement therapy for open angle glaucoma (OAG), migraine prophylaxis, and other conditions."
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