Therapist-guided smartphone-delivered CBT for Melancholia

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Massachusetts, Boston, MA
Melancholia+2 More
Mindset: Therapist-guided smartphone-delivered CBT - Behavioral
Eligibility
18+
All Sexes
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Study Summary

We are testing a smartphone app that provides therapy for depression. Participants will also receive short weekly virtual appointments with a therapist. Researchers want to know if this new treatment is usable, whether participants are satisfied with it, and whether it can help lower symptoms.

Eligible Conditions

  • Melancholia
  • Major Depressive Disorder (MDD)

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Melancholia

Study Objectives

6 Primary · 3 Secondary · Reporting Duration: Measured at baseline, week 4, week 8 (end of treatment)

Week 4
Change in Treatment Credibility (as measured by the CEQ)
Week 4
Change in Outcome Expectancy (as measured by the CEQ)
Week 8
Change in Functional impairment (as measured by the WSAS)
Change in Quality of life (as measured by the Q-LES-Q-SF)
Week 8
Change in MDD symptom severity (as measured by the HAM-D)
Week 8
App rating (as measured by the uMARS)
Week 8
Change in Patient Satisfaction (as measured by the CSQ-8)
Change in Treatment Utilization
Week 8
Drop-Out Rates

Trial Safety

Safety Progress

1 of 3

Other trials for Melancholia

Trial Design

1 Treatment Group

Therapist-guided smartphone-delivered CBT
1 of 1
Experimental Treatment

28 Total Participants · 1 Treatment Group

Primary Treatment: Therapist-guided smartphone-delivered CBT · No Placebo Group · N/A

Therapist-guided smartphone-delivered CBT
Behavioral
Experimental Group · 1 Intervention: Mindset: Therapist-guided smartphone-delivered CBT · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: measured at baseline, week 4, week 8 (end of treatment)

Trial Background

Sabine Wilhelm, PhD
Principal Investigator
Massachusetts General Hospital
Closest Location: Massachusetts · Boston, MA
Photo of Massachusetts General Hospital  1Photo of Massachusetts General Hospital  2Photo of Massachusetts General Hospital  3
2013First Recorded Clinical Trial
0 TrialsResearching Melancholia
5 CompletedClinical Trials

Eligibility Criteria

Age 18+ · All Participants · 4 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You live in Massachusetts.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.