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Active Treatment for Keratoconus (Apricity-A Trial)

Phase 3
Recruiting
Research Sponsored by Epion Therapeutics
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Diagnosis of keratoconus
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline to 12 months
Awards & highlights

Apricity-A Trial Summary

A Multicenter, Randomized, Double-Masked, Sham-Controlled, Parallel-Group Phase 3 Study to Evaluate the Efficacy and Safety of Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus

Apricity-A Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Apricity-A Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline to 12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Best Spectacle-Corrected Distance Visual Acuity (BSCDVA)
Secondary outcome measures
Vision-related Quality of Life as Assessed by the National Eye Institute 25-Item Visual Function Questionnaire (NEI-VFQ-25)

Apricity-A Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Active TreatmentExperimental Treatment1 Intervention
Epithelium-on corneal cross-linking
Group II: Control TreatmentPlacebo Group1 Intervention
Placebo and sham for epithelium-on corneal cross-linking

Find a Location

Who is running the clinical trial?

Epion TherapeuticsLead Sponsor
1 Previous Clinical Trials
400 Total Patients Enrolled
1 Trials studying Keratoconus
400 Patients Enrolled for Keratoconus
Michael Belin, MDStudy DirectorEpion Therapeutics
1 Previous Clinical Trials
400 Total Patients Enrolled
1 Trials studying Keratoconus
400 Patients Enrolled for Keratoconus

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus
2023. "Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06100939.
All > Vancouver > Madison
~267 spots leftby Oct 2025
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