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T Cell Immunotherapy for Multiple Myeloma
Study Summary
This trial is testing a new way to give immunotherapy after a stem cell transplant. Doctors will take some of the patient's immune cells, grow more of them in the lab, and then give them back to the patient.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
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Who is running the clinical trial?
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- I have been diagnosed with POEMS syndrome, non-secretory myeloma, plasma cell leukemia, or amyloidosis.I am approved for a stem cell transplant using my own cells.I am fully active or can carry out light work.My multiple myeloma has worsened or returned after treatment.I have had a stem cell transplant before.I have an autoimmune disease that needs treatment with medication.My condition was diagnosed as Stage II or III.I've had at least 3 cycles of chemotherapy or 3 months of high-dose steroids without my disease getting worse.I do not have severe heart, lung, kidney, liver, stomach, nerve, or mental health issues.I have not used corticosteroids in the last 21 days.I haven't taken antibiotics or antivirals in the last week.I have not had cancer, other than skin cancer or multiple myeloma, in the last 5 years.I have been diagnosed with multiple myeloma.I am between 18 and 70 years old.I am able to have children, tested negative for pregnancy, and will use birth control for 6 months.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is eligibility for the trial limited to people under fifty years of age?
"This research program is currently open to persons aged 18 or above, and no older than 70."
What are the eligibility criteria for participation in this medical trial?
"This clinical trial is searching for 35 individuals aged eighteen to seventy years old with multiple myeloma. To be eligible, patients must possess Durie-Salmon Stage II or III disease at any point since diagnosis and have completed induction therapy consisting of 3 chemotherapy cycles or a period of three months on high dose corticosteroids without witnessing progression in the condition. It's worth noting that glucocorticoid usage should not occur within three weeks prior to registration."
How many facilities are actively managing this experiment?
"The 6 sites conducting this trial are University of California, San Francisco in San Francisco, University of California, San Diego in San Diego, and Johns Hopkins Medical Institute in Baltimore. Additionally there are 3 other medical centres participating."
Is this scientific experiment in need of additional participants?
"Contrary to what's posted on clinicaltrials.gov, this medical trial is no longer recruiting participants; it was initially advertised October 1st 2002 and last edited November 6th 2006. Despite the cessation of recruitment for this study, 807 other trials are actively looking for qualified candidates right now."
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