Nicotinamide riboside for Aging
Phase-Based Progress Estimates
Effectiveness
Safety
University of Oklahoma Health Sciences Center, Oklahoma City, OK
Aging
Nicotinamide riboside - DrugEligibility
18+
All Sexes
What conditions do you have?
Select
Eligibility
18+
All Sexes
What conditions do you have?
Select
Study Summary
Daily consumption of one of the forms of Vitamin B3, the Nicotinamide Riboside (NR), energizes the body and combats cellular aging. This study is designed to test whether NR can also improve brain health and memory.
Treatment Effectiveness
Effectiveness Progress
This is further along than 93% of similar trials
Study Objectives
4 Primary · 15 Secondary · Reporting Duration: 8 weeks
8 weeks
Blood collection
Change in Attention
Change in ECG
Change in Episodic Memory
Change in Executive Function
Change in Glycocalyx - perfused boundary region
Change in Language
Change in Processing Speed
Change in Working Memory
Change in arterial stiffness
Change in capillary density
Change in deep tissue oxygen saturation
Change in macrovascular endothelial function
Change in microvascular endothelial function
Change in neuronal activity
Change in neurovascular coupling using functional near infrared spectroscopy (fNIRS)
Change in neurovascular coupling using the dynamic retinal vessel analysis
Change in neurovascular coupling using transcranial Doppler
Change in red blood cell velocity
Trial Safety
Safety Progress
This is further along than 85% of similar trials
Trial Design
2 Treatment Groups
NR
1 of 2
Control
1 of 2
Experimental Treatment
Non-Treatment Group
214 Total Participants · 2 Treatment Groups
Primary Treatment: Nicotinamide riboside · Has Placebo Group · Phase 4
NR
Drug
Experimental Group · 1 Intervention: Nicotinamide riboside · Intervention Types: DrugControl
Drug
PlaceboComparator Group · 1 Intervention: Placebo · Intervention Types: DrugTreatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Nicotinamide riboside
2014
Completed Phase 2
~90
Trial Logistics
Trial Timeline
Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 8 weeks
Closest Location: University of Oklahoma Health Sciences Center · Oklahoma City, OK
2002First Recorded Clinical Trial
1 TrialsResearching Aging
418 CompletedClinical Trials
Who is running the clinical trial?
University of OklahomaLead Sponsor
410 Previous Clinical Trials
95,392 Total Patients Enrolled
1 Trials studying Aging
148 Patients Enrolled for Aging
Oklahoma Medical Research FoundationOTHER
20 Previous Clinical Trials
7,693 Total Patients Enrolled
1 Trials studying Aging
148 Patients Enrolled for Aging
University of PennsylvaniaOTHER
1,797 Previous Clinical Trials
36,106,348 Total Patients Enrolled
3 Trials studying Aging
225,168 Patients Enrolled for Aging
Elysium HealthIndustry Sponsor
12 Previous Clinical Trials
1,503 Total Patients Enrolled
Eligibility Criteria
Age 18+ · All Participants · 5 Total Inclusion Criteria
Mark “yes” if the following statements are true for you:You have adequate hearing and visual acuity to participate in the examinations.
About The Reviewer
Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.
Popular Clinical Trials
Top Clinical Trials in Cities
Relevant Clinical Trials
Unbiased Results
We believe in providing patients with all the options.Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.Back to top
Conditions
Cancer Related
Treatments