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Mesenchymal Stromal Cells

hCT-MSC infusion for Autism Spectrum Disorder (TACT Trial)

Phase 1
Waitlist Available
Led By Joanne Kurtzberg, MD
Research Sponsored by Duke University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights

Summary

This trial will test the safety and effectiveness of a single infusion of hCT-MSC in toddlers with ASD.

Eligible Conditions
  • Autism Spectrum Disorder
  • Autism

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Clinical Global Impression Scale (CGI)
Change in Communicative Development Inventories (CDI-2)
Change in PDD Behavior Inventory Autism Composite Score (PDDBI)
+12 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: hCT-MSC infusionExperimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
hCT-MSC infusion
2017
Completed Phase 1
~30

Find a Location

Who is running the clinical trial?

Duke UniversityLead Sponsor
2,394 Previous Clinical Trials
3,059,474 Total Patients Enrolled
13 Trials studying Autism Spectrum Disorder
1,709 Patients Enrolled for Autism Spectrum Disorder
The Marcus FoundationOTHER
16 Previous Clinical Trials
1,524 Total Patients Enrolled
4 Trials studying Autism Spectrum Disorder
185 Patients Enrolled for Autism Spectrum Disorder
Joanne Kurtzberg, MD5.04 ReviewsPrincipal Investigator - Duke Health
Duke University
21 Previous Clinical Trials
773 Total Patients Enrolled
5 Trials studying Autism Spectrum Disorder
365 Patients Enrolled for Autism Spectrum Disorder
5Patient Review
Dr. Kurtzberg has been my physician for my entire life. I was born with an extremely rare cancer and was given 2 weeks at the most to live. Thanks to Dr. K's help in managing the side effects of the 8 chemotherapies and maximum amount of radiation one person can receive in their lifetime, I'm still here today. I'm truly grateful to have him as my doctor.
~3 spots leftby Jul 2025