← Back to Search

GABA-B Agonist

Arbaclofen for Autism Spectrum Disorder (ARBA Trial)

Phase 2
Waitlist Available
Led By Robert Nicolson, M.D
Research Sponsored by Evdokia Anagnostou
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 16 weeks
Awards & highlights

ARBA Trial Summary

This study is evaluating whether arbaclofen is safe and effective for improving social function in children and adolescents with ASD.

Eligible Conditions
  • Autism Spectrum Disorder
  • Autism

ARBA Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~16 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 16 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Vineland Adaptive Behavior Scales, Third Edition (Vineland-3) - Social Domain
Secondary outcome measures
Aberrant Behavior Checklist (ABC) - Social Withdrawal Subscale
Clinical Global Impressions - Impression Scale - Global (CGI-I-Global)
Clinical Global Impressions - Impression Scale - Improvement (CGI-I)
+4 more

ARBA Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: ArbaclofenActive Control1 Intervention
Group II: PlaceboPlacebo Group1 Intervention

Find a Location

Who is running the clinical trial?

University of TorontoOTHER
688 Previous Clinical Trials
1,018,460 Total Patients Enrolled
6 Trials studying Autism Spectrum Disorder
589 Patients Enrolled for Autism Spectrum Disorder
Evdokia AnagnostouLead Sponsor
11 Previous Clinical Trials
554 Total Patients Enrolled
10 Trials studying Autism Spectrum Disorder
535 Patients Enrolled for Autism Spectrum Disorder
Holland Bloorview Kids Rehabilitation HospitalOTHER
67 Previous Clinical Trials
13,984 Total Patients Enrolled
23 Trials studying Autism Spectrum Disorder
8,771 Patients Enrolled for Autism Spectrum Disorder

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

What site did they apply to?
McMaster University, Offord Centre for Child Studies
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
Arbaclofen vs. Placebo in the Treatment of Children and Adolescents With ASD (ARBA)
Evdokia Anagnostou 2019. "Arbaclofen vs. Placebo in the Treatment of Children and Adolescents With ASD (ARBA)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03887676.
~15 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top