Your session is about to expire
← Back to Search
GABA-B Agonist
Arbaclofen for Autism Spectrum Disorder (ARBA Trial)
Phase 2
Waitlist Available
Led By Evdokia Anagnostou, M.D
Research Sponsored by Evdokia Anagnostou
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be younger than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 16 weeks
Awards & highlights
Summary
This trial will test if arbaclofen can improve social skills in children and teenagers with Autism Spectrum Disorder (ASD). Currently, there are no medications specifically for social difficulties in ASD. Arbaclofen might help by balancing brain chemicals involved in social behavior. Previous trials have indicated the potential of arbaclofen for improving social function among autistic children and adolescents with fluent speech.
Eligible Conditions
- Autism Spectrum Disorder
- Autism
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 16 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~16 weeks
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Vineland Adaptive Behavior Scales, Third Edition (Vineland-3) - Social Domain
Secondary study objectives
Aberrant Behavior Checklist (ABC) - Social Withdrawal Subscale
Clinical Global Impressions - Impression Scale - Global (CGI-I-Global)
Clinical Global Impressions - Impression Scale - Improvement (CGI-I)
+4 moreTrial Design
2Treatment groups
Active Control
Placebo Group
Group I: ArbaclofenActive Control1 Intervention
Group II: PlaceboPlacebo Group1 Intervention
Find a Location
Who is running the clinical trial?
University of TorontoOTHER
706 Previous Clinical Trials
1,021,501 Total Patients Enrolled
6 Trials studying Autism Spectrum Disorder
589 Patients Enrolled for Autism Spectrum Disorder
Evdokia AnagnostouLead Sponsor
11 Previous Clinical Trials
554 Total Patients Enrolled
10 Trials studying Autism Spectrum Disorder
535 Patients Enrolled for Autism Spectrum Disorder
Holland Bloorview Kids Rehabilitation HospitalOTHER
67 Previous Clinical Trials
13,977 Total Patients Enrolled
23 Trials studying Autism Spectrum Disorder
8,771 Patients Enrolled for Autism Spectrum Disorder
Share this study with friends
Copy Link
Messenger