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SMS Text Messaging for Substance Use Disorders (TEXT2 Trial)

Led By Marina Tolou-Shams, PhD
Research Sponsored by University of California, San Francisco
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Ages 13-18
Be younger than 65 years old
Screening 3 weeks
Treatment Varies
Follow Up 180 days post baseline
Awards & highlights

TEXT2 Trial Summary

This trial will test whether sending text messages can help young people with substance abuse or mental health issues stay on track with their treatment.

Who is the study for?
This trial is for English-speaking youths aged 13-18 who are involved with the justice system and living in the community. They must have a mobile phone or tablet, be willing to send and receive texts, and be referred to substance use or mental health treatment along with having an adult caregiver.Check my eligibility
What is being tested?
The study tests if tailored SMS text messages can help improve attendance and engagement in treatment programs for youth dealing with substance use or dual diagnosis compared to standard care practices.See study design
What are the potential side effects?
Since this trial involves communication through text messaging rather than medication, there are no direct medical side effects. However, participants may experience increased stress or anxiety from receiving regular communications about their treatment.

TEXT2 Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
I am between 13 and 18 years old.

TEXT2 Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~180 days post baseline
This trial's timeline: 3 weeks for screening, Varies for treatment, and 180 days post baseline for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Treatment session attendance
Secondary outcome measures
First treatment session initiation
Other outcome measures
Alcohol use
Characteristics of Communication and Interaction with Probation Officers and Treatment Providers
Drug Use
+5 more

TEXT2 Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: SMS Text MessagingExperimental Treatment1 Intervention
SMS text messaging intervention for a period of 90 days to encourage attendance at community-based substance use or dual diagnosis treatment appointments through motivational messages.
Group II: Standard of Care Engagement PracticesActive Control1 Intervention
Standard of care engagement practices, such as communicating with youth and caregivers, as needed, through texting but frequency of contact and content of messaging varies according to individual needs.
First Studied
Drug Approval Stage
How many patients have taken this drug
SMS Text Messaging

Find a Location

Who is running the clinical trial?

National Institute on Drug Abuse (NIDA)NIH
2,502 Previous Clinical Trials
2,625,410 Total Patients Enrolled
68 Trials studying Substance Use
37,426 Patients Enrolled for Substance Use
University of California, San FranciscoLead Sponsor
2,527 Previous Clinical Trials
15,242,435 Total Patients Enrolled
6 Trials studying Substance Use
2,539 Patients Enrolled for Substance Use
Marina Tolou-Shams, PhDPrincipal InvestigatorUniversity of California, San Francisco
2 Previous Clinical Trials
420 Total Patients Enrolled

Media Library

SMS Text Messaging Clinical Trial Eligibility Overview. Trial Name: NCT04446910 — N/A
Substance Use Research Study Groups: SMS Text Messaging, Standard of Care Engagement Practices
Substance Use Clinical Trial 2023: SMS Text Messaging Highlights & Side Effects. Trial Name: NCT04446910 — N/A
SMS Text Messaging 2023 Treatment Timeline for Medical Study. Trial Name: NCT04446910 — N/A
~32 spots leftby Jun 2025