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Septic Shock Clinical Decision Support for Septic Shock

N/A

Waitlist Available

Led By Halden F Scott, MD, MSCS

Research Sponsored by University of Colorado, Denver

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 24 hours after emergency department arrival

Awards & highlights

Study Summary

This trial will test a tool to help ER doctors predict septic shock in kids. The goal is to see if the tool leads to better care for sepsis patients.

Eligible Conditions

Septic Shock
Sepsis
Emergency

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 24 hours after emergency department arrival

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 24 hours after emergency department arrival

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 24 hours after emergency department arrival for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Number of Patients Receiving Guideline-Concordant Septic Shock Care

Secondary outcome measures

Time to Antibiotics

Other outcome measures

30-Day In-Hospital Mortality

Number of Patients Receiving Intravenous Antibiotics during Emergency Department care

Number of Patients With Septic Shock

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Septic Shock Clinical Decision SupportExperimental Treatment1 Intervention

Emergency Department sites in this arm will have Clinical Decision Support (CDS) alerts active in the Electronic Health Record during clinical ED care of patients with suspected sepsis, in addition to following usual institutional standard of care for sepsis. The CDS will alert providers to patients at high risk for developing septic shock.

Group II: Clinical Diagnosis OnlyActive Control1 Intervention

Emergency Department sites in this arm will follow the institutional standard for sepsis care without Clinical Decision Support. Standard care includes clinical diagnosis of sepsis supported by institutional sepsis education, a sepsis pathway and orderset.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of Colorado, DenverLead Sponsor

1,732 Previous Clinical Trials

2,142,238 Total Patients Enrolled

Agency for Healthcare Research and Quality (AHRQ)FED

399 Previous Clinical Trials

6,821,003 Total Patients Enrolled

Halden F Scott, MD, MSCSPrincipal InvestigatorUniversity of Colorado, Denver

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment in this trial still a possibility for prospective participants?

"According to the data sourced from clinicaltrials.gov, this trial is actively seeking enrollees with a first posting date of March 16th 2022 and an updated post on March 17th 2022."

Answered by AI

What is the maximum cohort size for this medical study?

"Affirmative. Clinicaltrials.gov demonstrates that this clinical trial is presently recruiting participants, having been advertised on March 16th 2022 and last modified a day later. Three hundred thousand individuals are required to be enlisted from one medical centre."

Answered by AI

Recent research and studies

Pediatric Critical Care MedicineJournal

Development and Validation of a Model to Predict Pediatric Septic Shock Using Data Known 2 Hours After Hospital Arrival

Scott, Halden F., Kathryn L. Colborn, Carter J. Sevick, Lalit Bajaj, Sara J. Deakyne Davies, Diane Fairclough, Niranjan Kissoon, and Allison Kempe. 2020. “Development and Validation of a Model to Predict Pediatric Septic Shock Using Data Known 2 Hours After Hospital Arrival”. Pediatric Critical Care Medicine. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/pcc.0000000000002589.

The Journal of PediatricsJournal

Development and Validation of a Predictive Model of the Risk of Pediatric Septic Shock Using Data Known at the Time of Hospital Arrival

Scott, Halden F., Kathryn L. Colborn, Carter J. Sevick, Lalit Bajaj, Niranjan Kissoon, Sara J. Deakyne Davies, and Allison Kempe. 2020. “Development and Validation of a Predictive Model of the Risk of Pediatric Septic Shock Using Data Known at the Time of Hospital Arrival”. The Journal of Pediatrics. Elsevier BV. doi:10.1016/j.jpeds.2019.09.079.

clinicaltrials.govStudy

Implementation Trial of Predictive Modeling to Enhance Diagnosis and Improve Treatment in Pediatric Septic Shock

2022. "Implementation Trial of Predictive Modeling to Enhance Diagnosis and Improve Treatment in Pediatric Septic Shock". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05065333.