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Observational for Fallopian Tube Cancer

N/A
Recruiting
Led By Elizabeth Swisher
Research Sponsored by University of Washington
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion, up to 5 years
Awards & highlights

Study Summary

This study is being done to investigate clonal hematopoiesis and therapy-emergent myeloid neoplasms in patients with ovarian cancers. Researchers want to identify risk factors for developing these blood cancers as well as if there is/are a genetic/environmental component(s) to developing blood cancer.

Eligible Conditions
  • Peritoneal Carcinoma
  • Fallopian Tube Cancer
  • Ovarian Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion, up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, up to 5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Define the trajectories of clonal evolution and mechanisms of transformation from non-cancerous TP53m to TMN
Determine the correlation between baseline TP53m VAF in blood with CH expansion in OC patients
Identify risk of TMN for OC survivors with and without TP53m CH treated with platinum chemotherapy and PARP inhibitors

Trial Design

1Treatment groups
Experimental Treatment
Group I: ObservationalExperimental Treatment1 Intervention
Patients undergo blood sample collection and complete surveys on study. Patients' medical records are also reviewed.

Find a Location

Who is running the clinical trial?

National Cancer Institute (NCI)NIH
13,662 Previous Clinical Trials
40,923,881 Total Patients Enrolled
University of WashingtonLead Sponsor
1,740 Previous Clinical Trials
1,845,670 Total Patients Enrolled
Elizabeth SwisherPrincipal InvestigatorFred Hutch/University of Washington Cancer Consortium

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Clonal Hematopoiesis in Ovarian Cancer Survivors and Risk of Secondary Blood Cancers
2024. "Clonal Hematopoiesis in Ovarian Cancer Survivors and Risk of Secondary Blood Cancers". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06295965.
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~1333 spots leftby Dec 2028
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