Clonal Hematopoiesis for Blood Disorders
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores why some individuals with ovarian or other solid cancers develop blood cancers after treatment. Researchers examine blood samples and medical histories to identify any genetic or environmental causes of these blood cancers. The trial includes individuals who have had ovarian, peritoneal, or fallopian tube cancer and completed a specific amount of chemotherapy, as well as those with a solid tumor who have used certain cancer drugs or have certain blood disorders. Participants provide blood samples and share their medical records to help identify these risk factors. As an unphased trial, this study allows participants to contribute to groundbreaking research that could enhance the understanding and prevention of blood cancers.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Why are researchers excited about this trial?
Researchers are excited about this trial because it aims to uncover how clonal hematopoiesis—essentially changes in blood cells—might lead to myeloid neoplasms, a type of blood cancer, in cancer patients. Unlike standard treatments that directly target cancer cells, this study focuses on understanding underlying risk factors by analyzing blood samples and medical records. The goal is to identify potential early indicators of cancer development, which could lead to more personalized and preventative approaches in the future.
Who Is on the Research Team?
Elizabeth Swisher
Principal Investigator
Fred Hutch/University of Washington Cancer Consortium
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Observational
Patients undergo blood sample collection and complete surveys. Medical records are reviewed.
Follow-up
Participants are monitored for safety and effectiveness after observational activities
What Are the Treatments Tested in This Trial?
Interventions
- Non-Interventional Study
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Patients undergo blood sample collection and complete surveys on study. Patients' medical records are also reviewed.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Washington
Lead Sponsor
National Cancer Institute (NCI)
Collaborator
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