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Acetic Acid Supplement

Mizkan rice vinegar with acetic acid for Hypertension (Rice-vinegar Trial)

N/A
Waitlist Available
Led By Lydia Bazzano, MD, PhD
Research Sponsored by Mizkan Holdings Co., Ltd.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up weeks 4, 8, 12, and 16
Awards & highlights

Rice-vinegar Trial Summary

This study is to assess the blood pressure lowering effect of rice vinegar when consumed over a 12-week period by healthy adults ages 30-65 years old with prehypertension. Study subjects will be recruited online via ClaimIt software platform and randomized to receive either the active rice vinegar-based drink or placebo and will visit the Endothelix research study site in Houston, Texas, 6 times during the study (Week -2, 0, 4, 8, 12 and 16). Here, subjects will undergo blood pressure monitoring, endothelial function, and laboratory assessments.

Eligible Conditions
  • Hypertension

Rice-vinegar Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~weeks 4, 8, 12, and 16
This trial's timeline: 3 weeks for screening, Varies for treatment, and weeks 4, 8, 12, and 16 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Systolic Blood Pressure
Secondary outcome measures
Changes in Corresponding Blood Biomarkers
Changes in Diastolic Blood Pressure
Changes in Vascular Reactivity via VENDYS®
Other outcome measures
Assessment of Adverse Events
Changes in Body Weight and BMI
Changes in Dietary Intake
+2 more

Rice-vinegar Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Mizkan rice vinegar with acetic acidExperimental Treatment1 Intervention
200mL serving of a fruit-flavored beverage containing diluted Mizkan rice vinegar and 750mg acetic acid.
Group II: Mizkan rice vinegar without acetic acidPlacebo Group1 Intervention
200mL serving of a fruit-flavored beverage containing diluted Mizkan rice vinegar that has undergone a freeze-drying process to remove the acetic acid

Find a Location

Who is running the clinical trial?

EndothelixUNKNOWN
ObvioHealthIndustry Sponsor
11 Previous Clinical Trials
11,130 Total Patients Enrolled
Mizkan Holdings Co., Ltd.Lead Sponsor
1 Previous Clinical Trials
24 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
JamaJournal
The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure<subtitle>the JNC 7 Report</subtitle>
Chobanian, Aram V.. 2003. “The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressurethe JNC 7 Report”. Jama. American Medical Association (AMA). doi:10.1001/jama.289.19.2560.
CirculationJournal
Heart Disease and Stroke Statistics—2015 Update
Mozaffarian, Dariush, Emelia J. Benjamin, Alan S. Go, Donna K. Arnett, Michael J. Blaha, Mary Cushman, Sarah de Ferranti, et al.. 2015. “Heart Disease and Stroke Statistics—2015 Update”. Circulation. Ovid Technologies (Wolters Kluwer Health). doi:10.1161/cir.0000000000000152.
JamaJournal
The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure<subtitle>the JNC 7 Report</subtitle>
Chobanian, Aram V.. 2003. “The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressurethe JNC 7 Report”. Jama. American Medical Association (AMA). doi:10.1001/jama.289.19.2560.
clinicaltrials.govStudy
Rice Vinegar as an Intervention to Lower Blood Pressure in Adults With Prehypertension and 10-year CVD Risk <10%
2018. "Rice Vinegar as an Intervention to Lower Blood Pressure in Adults With Prehypertension and 10-year CVD Risk <10%". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03596099.
All > Blood Pressure
~20 spots leftby May 2025
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