Study Summary
This trial will study whether adding contrast to standard Endoscopic Ultrasound (EUS) improves the accuracy of diagnosing lesions and targeting biopsies in the pancreas.
- Pancreatic Cyst
- Pancreatic Cancer
- Pancreatitis
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 2 Secondary · Reporting Duration: 6 months
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
1 Treatment Group
Contrast EUS
1 of 1
Experimental Treatment
150 Total Participants · 1 Treatment Group
Primary Treatment: EUS enhanced with contrast to evaluate pancreas · No Placebo Group · N/A
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18 - 99 · All Participants · 1 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:- Săftoiu, Adrian, Peter Vilmann, Christoph F. Dietrich, Julio Iglesias-Garcia, Michael Hocke, Andrada Seicean, Andre Ignee, et al.. 2015. “Quantitative Contrast-enhanced Harmonic EUS in Differential Diagnosis of Focal Pancreatic Masses (with Videos)”. Gastrointestinal Endoscopy. Elsevier BV. doi:10.1016/j.gie.2014.11.040.
- Napoleon, B., M. Alvarez-Sanchez, R. Gincoul, B. Pujol, C. Lefort, V. Lepilliez, M. Labadie, et al.. 2010. “Contrast-enhanced Harmonic Endoscopic Ultrasound in Solid Lesions of the Pancreas: Results of a Pilot Study”. Endoscopy. Georg Thieme Verlag KG. doi:10.1055/s-0030-1255537.
- King, Kevin G., Mittul Gulati, Harshawn Malhi, Darryl Hwang, Inderbir S. Gill, Phillip M. Cheng, Edward G. Grant, and Vinay A. Duddalwar. 2015. “Quantitative Assessment of Solid Renal Masses by Contrast-enhanced Ultrasound with Time–intensity Curves: How We Do It”. Abdominal Imaging. Springer Science and Business Media LLC. doi:10.1007/s00261-015-0468-y.
- Kitano, Masayuki, Masatoshi Kudo, Kenji Yamao, Tadayuki Takagi, Hiroki Sakamoto, Takamitsu Komaki, Ken Kamata, et al.. 2012. “Characterization of Small Solid Tumors in the Pancreas: The Value of Contrast-enhanced Harmonic Endoscopic Ultrasonography”. American Journal of Gastroenterology. Ovid Technologies (Wolters Kluwer Health). doi:10.1038/ajg.2011.354.
- Săftoiu, Adrian, Peter Vilmann, Christoph F. Dietrich, Julio Iglesias-Garcia, Michael Hocke, Andrada Seicean, Andre Ignee, et al.. 2015. “Quantitative Contrast-enhanced Harmonic EUS in Differential Diagnosis of Focal Pancreatic Masses (with Videos)”. Gastrointestinal Endoscopy. Elsevier BV. doi:10.1016/j.gie.2014.11.040.
- King KG, Gulati M, Malhi H, Hwang D, Gill IS, Cheng PM, Grant EG, Duddalwar VA. Quantitative assessment of solid renal masses by contrast-enhanced ultrasound with time-intensity curves: how we do it. Abdom Imaging. 2015 Oct;40(7):2461-71. doi: 10.1007/s00261-015-0468-y.
- Saftoiu A, Vilmann P, Dietrich CF, Iglesias-Garcia J, Hocke M, Seicean A, Ignee A, Hassan H, Streba CT, Ioncica AM, Gheonea DI, Ciurea T. Quantitative contrast-enhanced harmonic EUS in differential diagnosis of focal pancreatic masses (with videos). Gastrointest Endosc. 2015 Jul;82(1):59-69. doi: 10.1016/j.gie.2014.11.040. Epub 2015 Mar 16.
- James Buxbaum 2016. "Contrast EUS of the Pancreas". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02863770.
Frequently Asked Questions
What is the maximum capacity for participants of this clinical experiment?
"Affirmative. As viewing from clinicaltrials.gov, this study is presently searching for participants. This trial was first listed on July 1st 2016 and most recently updated on December 6th 2021. The researchers are aiming to recruit 150 individuals across one site." - Anonymous Online Contributor
To what demographic is this research study open?
"Individuals with a pancreatic cyst and aged between 18-99 are eligible to join this clinical trial, which is limited to 150 participants." - Anonymous Online Contributor
Are there any vacancies available for participants in this clinical study?
"Clinicaltrials.gov confirms that this trial is currently in the process of enrolling study members, having first been advertised on July 1st 2016 and last updated December 6th 2021." - Anonymous Online Contributor
Does this trial offer participation to individuals aged sixty and over?
"This medical study is only available to those aged 18-99 years old. There are seventeen studies for minors and six hundred sixty one trials catering specifically to seniors." - Anonymous Online Contributor