WATS Sampling for Malignant Neoplasm of Stomach

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
The University of Alabama at Birmingham, Birmingham, AL
Malignant Neoplasm of Stomach+2 More
WATS Sampling - Device
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether the WATS approach is more effective than the Sydney protocol.

See full description

Eligible Conditions

  • Malignant Neoplasm of Stomach

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Malignant Neoplasm of Stomach

Study Objectives

This trial is evaluating whether WATS Sampling will improve 1 primary outcome and 1 secondary outcome in patients with Malignant Neoplasm of Stomach. Measurement will happen over the course of 36 months.

36 months
To compare the diagnostic yields of the WATS approach versus the updated Sydney protocol
To explore the performance of the existing and novel biomarkers, including the IHCs p53 and MUC2

Trial Safety

Safety Progress

1 of 3

Other trials for Malignant Neoplasm of Stomach

Trial Design

1 Treatment Group

Patients Scheduled for Standard of Care Upper Endoscopy
1 of 1
Experimental Treatment

This trial requires 300 total participants across 1 different treatment group

This trial involves a single treatment. WATS Sampling is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Patients Scheduled for Standard of Care Upper Endoscopy
Device

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 36 months
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 36 months for reporting.

Who is running the study

Principal Investigator
D. M.
Prof. Douglas Morgan, MD
University of Alabama at Birmingham

Closest Location

The University of Alabama at Birmingham - Birmingham, AL

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There is one eligibility criterion to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Patients with indication for upper endoscop

Patient Q&A Section

Has wats sampling proven to be more effective than a placebo?

"There was no significant difference between the two groups regarding pain reduction, bowel movements, stool consistency, and general well-being. Findings from a recent study of this study imply that there is a need for further studies with larger group sizes." - Anonymous Online Contributor

Unverified Answer

Have there been other clinical trials involving wats sampling?

"There are no previous randomized controlled clinical trials on wats sampling. Therefore, more randomized controlled clinical trials should be performed to evaluate the effect of wats sampling on patients' quality of life and survival." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets cancer of stomach?

"The most commonly reported peak ages for gastric cancer were 74 years for men and 75 years for women. Results from a recent clinical trial indicate that it is important for people who have either a family history or other risk factors for gastric cancer to be screened every two years by endoscopy, even if they do not have symptoms of the disease. Additionally, providers should recommend screening to patients after their 70th birthday, when there is an increased likelihood of finding a premalignant or malignant lesion." - Anonymous Online Contributor

Unverified Answer

Can cancer of stomach be cured?

"Carcinoma of stomach was found to be curable In a recent study. This finding supports earlier studies which showed that gastric carcinomas were curable. However, further investigations are required on the follow up procedures after removal of the primary tumor." - Anonymous Online Contributor

Unverified Answer

What are the signs of cancer of stomach?

"Symptoms depend on the type of cancer. The most common symptoms include abdominal pain, vomiting blood, nausea, weight loss, feeling tired, constipation, and diarrhea. The symptom and treatment of gastric cancer are as follows:\n\n- Abdominal pain is the first symptom of gastric cancer. According to the medical dictionary, "abdominal pain" is defined as "pain felt in the abdomen", including the right upper quadrant of the abdomen, which is where most tumors occur. Tumors may lie directly on the liver, spleen, pancreas, kidneys, and intestines. Gastric cancer may also affect the digestive tract." - Anonymous Online Contributor

Unverified Answer

What does wats sampling usually treat?

"The exact staging criteria need to be defined for Wats' sampling in order to ensure an optimal selection of patients who will benefit from it. Moreover, this approach should be multi-centre and prospective." - Anonymous Online Contributor

Unverified Answer

What causes cancer of stomach?

"Cancer of stomach is associated with chronic inflammation due to Helicobacter pylori infection. The risk factors for cancer of stomach include smoking, alcoholism, obesity, high blood pressure, diabetes mellitus, familial adenomatous polyposis, and hyperlipidemia." - Anonymous Online Contributor

Unverified Answer

Who should consider clinical trials for cancer of stomach?

"Recent findings of this study suggest that, among all patients with gastric cancer, no subgroup of patients would benefit more from enrollment in a prospective randomized clinical trial compared with standard care alone." - Anonymous Online Contributor

Unverified Answer

How does wats sampling work?

"The amount of biologically relevant information contained in the WATS sample was comparable to that obtained from conventional biopsies. In conclusion, we suggest that WATS sampling should be performed routinely to obtain additional information from pancreatic cancers." - Anonymous Online Contributor

Unverified Answer

Does cancer of stomach run in families?

"Findings from a recent study indicated that genetic factors might have played more important roles than environment in carcinogenesis of gastric cancer in this family. Findings from a recent study of our study provide a clue for future investigations in hereditary gastric cancer." - Anonymous Online Contributor

Unverified Answer

Is wats sampling typically used in combination with any other treatments?

"Wats sampling is often used as an adjunct to chemotherapy and radiation therapy for gastric cancer. Additional investigations are required to better understand its role." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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