WATS Sampling for Stomach Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this research is to compare the diagnostic yields of the WATS approach versus the updated Sydney protocol (five standard biopsies in the three gastric regions).• We hypothesize that the WATS technology will increase the overall diagnostic yield up to 35% of gastric premalignant lesions and early gastric cancer.To explore the performance of the existing and novel biomarkers, including the IHCs p53 and MUC2.We anticipate concordance of the existing biomarkers as adjuncts to the diagnosis.To accomplish this aim, we will analyze current biomarkers on all study subjects (Aim 1), as well as explore novel gastric biomarkers.
Who Is on the Research Team?
Douglas Morgan, MD
Principal Investigator
University of Alabama at Birmingham
Are You a Good Fit for This Trial?
This trial is for patients who need an upper endoscopy, which is a procedure where a doctor looks inside the stomach. It's designed to test if a new way of sampling cells from the stomach lining can better detect early signs of cancer or precancerous conditions compared to current methods.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo wide-area trans-epithelial gastric sampling using WATS technology and standard biopsies for diagnostic comparison
Follow-up
Participants are monitored for safety and effectiveness after treatment, including analysis of biomarkers
What Are the Treatments Tested in This Trial?
Interventions
- WATS Sampling
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Alabama at Birmingham
Lead Sponsor