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Contingency Management for Opioid Use Disorder

N/A
Waitlist Available
Led By August Holtyn
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 weeks
Awards & highlights
No Placebo-Only Group

Study Summary

This trial will compare the effectiveness of two different contingency management interventions for treating adults with opioid use disorder.

Who is the study for?
This trial is for adults with opioid use disorder who are currently enrolled in buprenorphine treatment. Participants must be willing and able to use a smartphone, as the study involves remote verification of medication adherence and abstinence through video.Check my eligibility
What is being tested?
The study tests two Contingency Management strategies against Standard Medical Management. One group gets incentives for taking buprenorphine daily, another also gets rewards for opiate-free saliva samples, while the third receives usual care without these incentives.See study design
What are the potential side effects?
Since this trial focuses on behavioral interventions rather than medications, there are no direct side effects from drugs being tested. However, participants may experience stress or disappointment if they do not meet goals and miss out on incentives.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Buprenorphine adherence as assessed by the percentage of buprenorphine-positive urine samples
Opiate abstinence as assessed by the percentage of opiate-negative urine samples
Secondary outcome measures
Buprenorphine diversion as assessed by the rates at which participants report diverting participants' buprenorphine

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Buprenorphine Adherence and Opiate AbstinenceExperimental Treatment2 Interventions
Participants will receive financial incentives for buprenorphine use and opiate abstinence.
Group II: Buprenorphine Adherence OnlyExperimental Treatment1 Intervention
Participants will receive financial incentives for buprenorphine use.
Group III: ControlActive Control1 Intervention
Participants will not receive any intervention.

Find a Location

Who is running the clinical trial?

Patient-Centered Outcomes Research InstituteOTHER
543 Previous Clinical Trials
29,988,168 Total Patients Enrolled
Johns Hopkins UniversityLead Sponsor
2,221 Previous Clinical Trials
14,811,094 Total Patients Enrolled
August HoltynPrincipal InvestigatorJohns Hopkins University
1 Previous Clinical Trials
60 Total Patients Enrolled

Media Library

Contingency Management for adherence Clinical Trial Eligibility Overview. Trial Name: NCT04024059 — N/A
Opioid Use Disorder Research Study Groups: Buprenorphine Adherence Only, Control, Buprenorphine Adherence and Opiate Abstinence
Opioid Use Disorder Clinical Trial 2023: Contingency Management for adherence Highlights & Side Effects. Trial Name: NCT04024059 — N/A
Contingency Management for adherence 2023 Treatment Timeline for Medical Study. Trial Name: NCT04024059 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are geriatric patients accepted into this trial?

"As per the criteria for inclusion, prospective participants must be no younger than 18 and not older than 100 years of age."

Answered by AI

Could I be a volunteer for this clinical exploration?

"This clinical trial is accepting 375 applicants with opioid use disorder (OUD) who are between 18 and 100 years old. The primary prerequisites for admittance to the study include: being diagnosed with OUD, as well as currently participating in buprenorphine treatment."

Answered by AI

Are there any unfilled vacancies in this trial for volunteer participants?

"Affirmative. According to the information available on clinicaltrials.gov, this study is currently seeking patient volunteers and was first published on January 31st 2020 before being edited as recently as May 6th 2022. The trial requires 375 participants from a single clinic site."

Answered by AI

How many individuals are engaged in this clinical experiment?

"That is correct. The clinicaltrials.gov website verifies that this experiment, which was initially posted on January 31st 2020, is currently sourcing participants. 375 volunteers must be sourced from a single trial site."

Answered by AI

Who else is applying?

What state do they live in?
Washington
How old are they?
18 - 65
What site did they apply to?
Center for Learning and Health
What portion of applicants met pre-screening criteria?
Met criteria
~75 spots leftby Feb 2025