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Acute Pain's Impact on Cognitive Performance
Study Summary
This trial investigates whether acute pain impairs cognitive performance, such as working memory, attention and processing speed.
- Cognition
- Acute Pain
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Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2016 Phase 4 trial • 120 Patients • NCT03124407Trial Design
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Who is running the clinical trial?
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- You have a history of or currently have mental health conditions, learning disabilities, or cognitive impairments like severe anxiety, severe depression, or autism spectrum disorder.Your score on the MoCA test is less than 23.Your resting heart rate is either too slow (less than 50 beats per minute) or too fast (more than 100 beats per minute).Your resting blood pressure is too low (less than 90/60) or too high (more than 140/95).You are currently taking four or more medications.Your score on the GAD-7 anxiety questionnaire is 10 or higher.You have a score of 2 or more on the PHQ-2 and a score of 10 or more on the PHQ-9.You have had ongoing health issues in the past three months, including problems with muscles and bones, the heart, hormones, lungs, metabolism, mental health, or the nervous system.You have a medical device like a pacemaker or neurostimulator implanted in your body.You have sensitive skin that reacts to soaps, creams, perfumes, or heat.You have taken part in a study about movement and learning in this lab in the last 2 years.You are between 18 and 35 years old.You are allergic to spicy foods or hot peppers.You have reduced feeling or strength in your legs or in the area being tested.You have a history of balance problems, dizziness, or more than one fall in the past year.You have had a severe head injury where you lost consciousness for more than 5 minutes or needed medical treatment, or you have had more than 2 concussions in your life.You are currently taking pain relief medications regularly, including over-the-counter remedies.You have poor blood flow in the area where the pain will be tested.You have had ongoing pain anywhere in your body for the past year.You have any skin issues in the area where the pain will be tested.
- Group 1: Pain Stimulus
- Group 2: Distractor Somatosensory Stimulus
- Group 3: No Stimulus
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Does this experiment accept participants eighteen years or older?
"The age requirement for participation in this clinical study is 18 to 35 years old."
Is enrollment for this research experiment still open?
"Yes, this trial remains open as indicated on clinicaltrials.gov. Its original posting was made on April 5th 2023 and it has been updated more recently on May 9th of the same year."
How many participants are being assessed in this research project?
"Affirmative. The information found on clinicaltrials.gov reveals that this trial, which was originally posted on April 5th 2023, is actively enlisting participants. 50 volunteers are needed at a single site to complete the study."
What are the primary goals of this medical experiment?
"The primary measure of the trial's success is based on Trail Making Test A & B progress between baseline and delivery. Secondary outcomes include verbal fluency, Wisconsin Card Sorting Test accuracy, and NIH Toolbox List Sorting recall and sequencing capability."
Is it feasible for me to partake in this research project?
"This experiment is seeking 50 participants in the 18-35 years old age range who currently experience acute pain. To qualify, individuals must be literate and fluent speakers of English; provide voluntary consent; possess self-reported good health; and agree to accept either experimental or non-painful electrical stimulation if chosen. Additionally, prospective test subjects should meet any other criteria outlined by HR (heart rate), bpm (beats per minute), BP (blood pressure), ADD/ADHD (Attention Deficit Disorder / Attention Deficit Hyperactivity Disorder) scores on MoCA/GAD-7/PHQ2/PHQ9 tests"
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