Selective Therapy: Drug for Kidney Stones
Phase-Based Progress Estimates
Effectiveness
Safety
Vanderbilt University Medical Center, Nashville, TN
Kidney Stones+2 More
Selective Therapy: Drug - DrugEligibility
18+
All Sexes
What conditions do you have?
Select
Eligibility
18+
All Sexes
What conditions do you have?
Select
Study Summary
The aims of this study are to 1) Conduct a randomized clinical trial of selective versus empiric diet plus pharmacologic therapy in high-risk stone formers and 2) Determine adverse effects from, and adherence to selective and empiric strategies.
Eligible Conditions
- Kidney Stones
- Nephrolithiasis
Treatment Effectiveness
Effectiveness Progress
This is further along than 93% of similar trials
Study Objectives
2 Primary · 2 Secondary · Reporting Duration: Baseline compared to two months
Month 2
24hr urine parameters from month 1 to month 2
Baseline compared to two months
24hr urine parameters
Calcium oxalate supersaturation
Calcium phosphate supersaturation
Uric acid supersaturation
Baseline to 1 month
24hr urine parameters from baseline to month 1
Baseline to 2 months
Adverse events
Diet adherence
Diet and medication adherence
Kidney stone events
Medication adherence
Trial Safety
Safety Progress
This is further along than 85% of similar trials
Trial Design
2 Treatment Groups
Empiric Therapy
1 of 2
Selective Therapy
1 of 2
Active Control
Experimental Treatment
56 Total Participants · 2 Treatment Groups
Primary Treatment: Selective Therapy: Drug · No Placebo Group · Phase 4
Selective TherapyExperimental Group · 2 Interventions: Selective Therapy: Diet, Selective Therapy: Drug · Intervention Types: Behavioral, Drug
Empiric TherapyActiveComparator Group · 2 Interventions: Empiric Therapy: Drug, Empiric Therapy: Diet · Intervention Types: Drug, Behavioral
Trial Logistics
Trial Timeline
Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline compared to two months
Closest Location: Vanderbilt University Medical Center · Nashville, TN
2006First Recorded Clinical Trial
5 TrialsResearching Kidney Stones
1026 CompletedClinical Trials
Who is running the clinical trial?
Vanderbilt University Medical CenterLead Sponsor
758 Previous Clinical Trials
590,031 Total Patients Enrolled
3 Trials studying Kidney Stones
223 Patients Enrolled for Kidney Stones
Ryan Hsi, MDPrincipal InvestigatorVanderbilt University Medical Center
2 Previous Clinical Trials
280 Total Patients Enrolled
1 Trials studying Kidney Stones
80 Patients Enrolled for Kidney Stones
Eligibility Criteria
Age 18+ · All Participants · 2 Total Inclusion Criteria
Mark “yes” if the following statements are true for you:You have two or more symptomatic kidney stone events in the last 5 years.
About The Reviewer
Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.
Popular Clinical Trials
Top Clinical Trials in Cities
Relevant Clinical Trials
Unbiased Results
We believe in providing patients with all the options.Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.Back to top
Conditions
Cancer Related
Treatments