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Electrical Stimulation

Intraoperative Cochlear Nerve Stimulation for Acoustic Neuroma

N/A

Recruiting

Led By John C Middlebrooks, PhD

Research Sponsored by University of California, Irvine

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Adults with the diagnosis of unilateral or bilateral vestibular schwannoma proven on radiographic imaging.

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up recorded immediately during ongoing cochlear-nerve stimulation

Awards & highlights

Study Summary

This trial will test if it is possible to stimulate the auditory system by placing an electrode next to the cochlear nerve.

Who is the study for?

This trial is for adults diagnosed with vestibular schwannoma, confirmed by imaging scans. It's specifically for those who have little to no hearing and are undergoing surgery to remove the tumor. Pregnant women cannot participate.Check my eligibility

What is being tested?

The study is testing the possibility of stimulating the auditory system using an electrode that directly contacts the cochlear nerve during surgery for vestibular schwannoma.See study design

What are the potential side effects?

Potential side effects may include discomfort at the stimulation site, temporary changes in residual hearing, or altered sensation within the ear post-operation.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have a tumor on my balance nerve confirmed by imaging tests.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ recorded immediately during ongoing cochlear-nerve stimulation

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~recorded immediately during ongoing cochlear-nerve stimulation

This trial's timeline: 3 weeks for screening, Varies for treatment, and recorded immediately during ongoing cochlear-nerve stimulation for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Auditory brainstem response

Trial Design

1Treatment groups

Experimental Treatment

Group I: Intraoperative electrical stimulation of cochlear nerveExperimental Treatment1 Intervention

Electrical stimulation of the cochlear nerve will be tested intraoperatively in patients undergoing vestibular schwannoma resection.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of California, IrvineLead Sponsor

542 Previous Clinical Trials

1,921,993 Total Patients Enrolled

John C Middlebrooks, PhDPrincipal InvestigatorUniversity of California, Irvine

Harrison M Lin, MDPrincipal InvestigatorUniversity of California, Irvine

Media Library

Electrical stimulation of cochlear nerve (Electrical Stimulation) Clinical Trial Eligibility Overview. Trial Name: NCT05248113 — N/A

Hearing Loss Research Study Groups: Intraoperative electrical stimulation of cochlear nerve

Hearing Loss Clinical Trial 2023: Electrical stimulation of cochlear nerve Highlights & Side Effects. Trial Name: NCT05248113 — N/A

Electrical stimulation of cochlear nerve (Electrical Stimulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05248113 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this clinical research still accepting participants?

"According to clinicaltrials.gov, this research trial is actively seeking enrolment of participants. The study's inception was on the 25th of January 2022 with its most recent update being posted towards the end of November in the same year."

Answered by AI

Does this clinical experiment encompass individuals aged 55 or older?

"According to the requirements for this research, individuals aged 18 and above, but below 99 years old are allowed to enroll."

Answered by AI

Are there certain criteria for individuals to be eligible for this experimental research?

"This clinical trial is searching for 8 people, ranging from 18 to 99 years old who have hearing impairment. Additionally, those wishing to participate must also satisfy the following requirements: having a unilateral or bilateral vestibular schwannoma confirmed through imaging techniques and minimal auditory capacity while undergoing surgery related to this tumor."

Answered by AI

How many individuals are being enrolled in this clinical research program?

"Absolutely. Clinicaltrials.gov provides evidence that this research is currently recruiting participants, with postings dating back to the 25th of January 2022 and a recent update on November 28th 2022. 8 enrollees are required for the single clinical site associated with this study."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Intraoperative Electrically-evoked ABRs in Patients Undergoing Vestibular Schwannoma Surgery

Harrison W Lin 2022. "Intraoperative Electrically-evoked ABRs in Patients Undergoing Vestibular Schwannoma Surgery". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05248113.

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