Control Lens B for Myopia
This study is evaluating whether a silicone hydrogel contact lens can be worn for a month.
See full descriptionAbout the trial for Myopia
Treatment Groups
This trial involves 2 different treatments. Control Lens B is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
About The Treatment
Eligibility
This trial is for patients born any sex between 18 and 65 years old. There are 10 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether Control Lens B will improve 1 primary outcome in patients with Myopia. Measurement will happen over the course of Day 27.
Patient Q & A Section
What is myopia?
In a recent study, findings showed that myopia was an increasingly present problem among Chinese children and adolescents, with high prevalence for far-sightedness. We also found that there was an association between myopia and obesity, dyslipidemia and DM.
What causes myopia?
The condition of the eye (primarily, intraocular pressure), the light environment, a number of genes and hormones, the brain, and many other factors can determine the amount of vision achievable. Myopia is a common condition with a range of causes.
What are common treatments for myopia?
Myopia and the management of myopic refractive errors are well understood and have traditionally been treated primarily with myopic contact lenses. In many places, the use of ophthalmic eyeglasses have become common in the management of myopia. At the time of eye exam, patients are often advised to wear eyeglasses for prevention of amblyopia and to increase near-point clarity of distance vision. However, current studies evaluating the effect of myopic eyeglasses on distance vision or near-point clarity provide mixed results.
How many people get myopia a year in the United States?
The number of people who develop myopia in the United States is about half that of people with diabetes and one-fifth that of people who have heart disease. The increased prevalence of myopia among children and adolescents underscores the importance of preventive efforts.
What are the signs of myopia?
Any of these symptoms can indicate the presence of either myopia or astigmatism. An ophthalmologic examination is recommended to clarify if the cause is myopia or astigmatism.
Can myopia be cured?
Myopia cannot be (or is not) cured by any of the currently available therapies including refractive surgery. Myopathy appears to be a separate clinical entity, while asthenopia is a more common symptom. Neither myopia, myopathy nor asthenopia can be cured.
Is control lens b safe for people?
There is a general acceptance amongst the reflux lens providers and their patients that the b lens has a wider dynamic range than expected. It should be used with caution.
Have there been other clinical trials involving control lens b?
There have not been any previous clinical trials with control lenses. No conclusive evidence has been found when performing refraction on children younger than 6 years of age with myopia. There have been very few uncontrolled case series involving the use of children with severe myopia to demonstrate the refractive benefits of other control lens combinations. There are also few controlled studies documenting the efficacy of using other control lenses for myopic children during their active refractive growth period. There are currently no guidelines in existence for when and how well children with high myopia can participate in clinical studies.
What are the common side effects of control lens b?
In the current study, side effects of control lens b and silicone hydrogel contact lenses in the long term were moderate or mild in most cases.
What is control lens b?
The lens b of the NAGRA group was close to the target and lens b was independent of lens power. However, we recommend that doctors keep long-term follow up of visual functions, such as the reading and vision scores to look at the lens image displacement, and we need a prospective study to investigate whether there is an increased risk of developing cataracts in patients with a history of myopia who have undergone lens implantation.
Who should consider clinical trials for myopia?
This research suggests that both low and high myopia are equally common in India. The majority in this research did not seek myopia treatment in any form. The low willingness of treating myopia is quite alarming. This suggests a larger number of cases with untreated myopia. These numbers warrant consideration for treatment options such as refractive surgery and medical therapy such as atropine. The low willingness to seek treatment may be a problem for future management of myopia in India, as patients may be wary of treatment options.
How does control lens b work?
The control lens can function well for an extended period with little deterioration of the refractive power. This means that the control lens can be more comfortable for the patient, avoiding a refractive error which can be corrected by lenses.