Study Summary
This trial will compare two methods of removing IUDs with missing strings and measure patient/provider satisfaction, pain, time, and complications. Results may improve access and expand options for IUD removal.
- Intrauterine Device Threads Not Visible
- Intrauterine Device Removal Complication
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 1 Secondary · Reporting Duration: 12-18 months
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
2 Treatment Groups
Removal with manual vacuum aspiration
1 of 2
Removal with alligator forceps
1 of 2
Experimental Treatment
75 Total Participants · 2 Treatment Groups
Primary Treatment: Removal with manual vacuum aspiration · No Placebo Group · N/A
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18 - 45 · Female Participants · 2 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:- Prabhakaran S, Chuang A. In-office retrieval of intrauterine contraceptive devices with missing strings. Contraception. 2011 Feb;83(2):102-6. doi: 10.1016/j.contraception.2010.07.004. Epub 2010 Aug 23. No abstract available.
- Marchi NM, Castro S, Hidalgo MM, Hidalgo C, Monteiro-Dantas C, Villarroeal M, Bahamondes L. Management of missing strings in users of intrauterine contraceptives. Contraception. 2012 Oct;86(4):354-8. doi: 10.1016/j.contraception.2012.01.018. Epub 2012 Mar 27.
- Verma U, Astudillo-Davalos FE, Gerkowicz SA. Safe and cost-effective ultrasound guided removal of retained intrauterine device: our experience. Contraception. 2015 Jul;92(1):77-80. doi: 10.1016/j.contraception.2015.02.008. Epub 2015 Feb 21.
- Swenson C, Royer PA, Turok DK, Jacobson JC, Amaral G, Sanders JN. Removal of the LNG IUD when strings are not visible: a case series. Contraception. 2014 Sep;90(3):288-90. doi: 10.1016/j.contraception.2014.04.007. Epub 2014 Apr 21.
- Mizia K, Ramsay P. The effectiveness and safety of ultrasound-guided removal of a Mirena((R)) intrauterine system when the strings are not visible and conventional office procedures have failed. Aust N Z J Obstet Gynaecol. 2013 Aug;53(4):386-8. doi: 10.1111/ajo.12103. Epub 2013 Jun 26.
- da Silva Nobrega AB, Pitangui ACR, Vieira CS. Factors associated with missing strings and expulsion after postplacental insertion of copper T380A intrauterine devices. Int J Gynaecol Obstet. 2022 Apr;157(1):67-75. doi: 10.1002/ijgo.13806. Epub 2021 Jul 27.
- Wu JP, Porch E, Womack JP. Successful retrieval of an intrauterine device with "missing strings" using a manual vacuum aspirator in a desired early pregnancy: case report. J Minim Invasive Gynecol. 2011 Mar-Apr;18(2):254-6. doi: 10.1016/j.jmig.2010.11.008.
- Jain A, Singh S, Elliyas S. Effectiveness of Manual Vacuum Aspiration (MVA) Device in the Management of Intrauterine Copper Devices (IUCD) with Missing Strings: A Prospective Interventional Study. J Obstet Gynaecol India. 2021 Aug;71(4):424-429. doi: 10.1007/s13224-021-01440-x. Epub 2021 Mar 15.
- Guillebaud J, Kasonde JM. A simple scheme for managing the problem of 'lost threads' with intrauterine devices. Fertil Contracept. 1979 Apr;3(2):24-32.
- 2023. "A Randomized Controlled Trial of No Strings Intrauterine Device (IUD) Removal Techniques". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05702242.
Frequently Asked Questions
Are octogenarians permitted to apply for this research experiment?
"Based on the given conditions, individuals between 18 and 45 years old may be eligible to participate in this trial." - Anonymous Online Contributor
Are new participants being accepted to take part in this trial?
"The clinical trial database lists this study as actively searching for participants. The initial post date was January 1, 2023 with the most recent update on January 17th of that same year." - Anonymous Online Contributor
What criteria must be met in order to participate in this research program?
"Qualifying candidates for this clinical investigation must demonstrate non-detectable intrauterine device threads and be within the ages of 18 to 45. A total of 75 patients are expected to take part in this trial." - Anonymous Online Contributor
How many participants are partaking in this research?
"Affirmative. According to the details provided on clinicaltrials.gov, this trial is actively enrolling participants from one site since it was first published in January 1st 2023 and last updated on January 17th 2023. A total of 75 people are needed for the study." - Anonymous Online Contributor