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Procedure

LVHR PFC for Ventral Hernia

N/A
Waitlist Available
Led By Mike K Liang, MD
Research Sponsored by The University of Texas Health Science Center, Houston
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years after surgery
Awards & highlights

Study Summary

This study is comparing the outcomes patients undergoing LVHR, PFC as opposed to a bridged repair with assessment of patient reported satisfaction and function at 6 months of follow-up.

Eligible Conditions
  • Ventral Hernia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~30 days after surgery
This trial's timeline: 3 weeks for screening, Varies for treatment, and 30 days after surgery for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Patient Satisfaction and function
Secondary outcome measures
Clinical bulging/eventration
Hernia recurrence and clinical bulging/eventration
Surgical site infection

Trial Design

2Treatment groups
Experimental Treatment
Group I: LVHR PFCExperimental Treatment1 Intervention
Ventral hernia repairs in the primary fascial group will be performed similarly except prior to placement of the mesh, the defect will be closed. After the defect size is measured, the mesh will be chosen based upon the unclosed defect size and size will not be adjusted. The hernia defect will be closed as described previously 9,10 with 0-prolene transfascial sutures placed every 1-2 cm. The two caudal-most and cranial-most sutures will be placed. The abdomen will be desufflated and these sutures will be secured. The abdomen will be reinsufflated to 15 mm Hg and the defect progressively closed. Upon completion of fascial closure, the mesh will be placed in the standard fashion as describe above. The lateral overlap will be increased due to the fascial closure.
Group II: Bridging LVHRExperimental Treatment1 Intervention
Laparoscopic ventral hernia repair without closure of central defect (bridging repair) Upon completion of the lysis of adhesions, the margins of the hernia defect will be measured and marked. The hernia defect size will be measured with the abdomen completely desufflated and insufflated at 15 mm Hg externally (on the skin). A coated mesh with at least four cm of overlap on all sides will be placed. Mesh will be secured with at least four but no more than eight trans-fascial sutures. Titanium tacks will be placed in a double crown technique where tacks are placed every 1 cm on the periphery and every 3 cm along the fascial edge (bridged or closed).

Find a Location

Who is running the clinical trial?

The University of Texas Health Science Center, HoustonLead Sponsor
904 Previous Clinical Trials
320,808 Total Patients Enrolled
Mike K Liang, MDPrincipal InvestigatorThe University of Texas Health Science Center, Houston
2 Previous Clinical Trials
434 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Primary Fascial Closure With Laparoscopic Ventral Hernia Repair: A Randomized Controlled Trial
Mike K Liang 2015. "Primary Fascial Closure With Laparoscopic Ventral Hernia Repair: A Randomized Controlled Trial". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02363790.
All > Hernia
~19 spots leftby Apr 2025
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