This trial is evaluating whether LiquiBand FIX8® will improve 1 primary outcome and 6 secondary outcomes in patients with Hernia, Femoral. Measurement will happen over the course of At the time of surgery..
This trial requires 284 total participants across 2 different treatment groups
This trial involves 2 different treatments. LiquiBand FIX8® is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"Approximately 2.5 million cases of all forms of femoral hernias occur each year. The most frequent location of hernia is the groin region, with hernias occurring most commonly in women of childbearing age." - Anonymous Online Contributor
"Symptoms of a hernia in a child include a bulging groin, groin pain, weakness of the thigh muscle, feeling that the testicles have fallen through the groin, and feeling that the testicles are moving or moving up and down. Sudden weakening of the thigh muscle and reduced movement of the thigh are more suggestive of a strangulated hernia. Symptoms typically appear during the first five to six months of life. On the abdominal examination, a strangulated hernia can be verified by finding a bulging bulge, and the testicles must lie within the inguinal canal (between and above the scrotum)." - Anonymous Online Contributor
"Many patients with groin hernia or femoral vein thrombosis have been treated with a combination of antibiotics, anticoagulants, and thrombolytics, sometimes in outpatient settings. The use of these medications appears to be associated with prolongation of hospital stays and high rates of serious complications. Antibiotics, anticoagulants, and thrombolytics must not be used clinically for routine treatment of groin hernia and femoral vein thrombosis in an outpatient setting. Appropriate treatment for groin hernia and femoral vein thrombosis may involve medical management with a combination of low-dose heparin and/or compression stockings and surgery." - Anonymous Online Contributor
"The most plausible explanation for the observed findings is that the hernias represent the same anatomical entity as the femoral hernias. The herniation process seems to be related to the muscular structure of the aponeurosis of the femoral nerve or the muscular tissue of the inguinal canal. The herniation is not a result of a congenital defect, but may be developed after trauma, which causes a disruption of the nerve and ligamentous structures. Alternatively, it may be associated with anatomical anomalies, such as intestinal malrotation. Since hernias seem to be associated with an increase in abdominal circumference, it is also interesting to consider a correlation between hernias and body weight." - Anonymous Online Contributor
"While a significant number of hernia syndromes can be cured through proper repair, the most rewarding form of treatment is to find the cause of the hernia via the correct examination. At this time, hernioplasty is a palliative procedure and cannot be considered a cure for the underlying disorder." - Anonymous Online Contributor
"A hernia may be an abdominal organ protruding through the inner of the thigh, it is an extremely common disorder and most common among women." - Anonymous Online Contributor
"[Hernia, femoral] clinical research should concentrate on developing a treatment plan that incorporates existing research and is as simple as possible. To achieve this, an effective communication between researchers and hospitals is essential." - Anonymous Online Contributor
"The majority of patients use Liquibalcon fix8(®) in conjunction with multiple other treatments. Combining Liquibalcon fix8(®) with multiple treatments can be more beneficial to patients with groin hernias." - Anonymous Online Contributor
"The medical community still has much to learn and further research is necessary in order to find out the best surgical treatment for hernia, femoral. Recent research has shown the effect of using the natural compounds, plant extracts, and herbal formulas on hernia, femoral. As many of the above mentioned compounds have been shown not only to decrease the progression of the condition, but also alleviate the pain caused by the herniated organ, they act as the best surgical treatment. There is also still a great need for researchers to continue studying to find out how we can use the natural compounds to treat hernia, femoral." - Anonymous Online Contributor
"Using a preoperative evaluation and surgical placement of 4 ml of Ligumab 8% solution, nearly 90% of patients were unable to find any difference in pain, function, strength, or range of motion when compared to preoperative evaluation and surgical placement without Ligumab 8% solution. Injectant, but not Ligumab 8% solution did produce significant decreases in pain, range of motion, and strength when compared to preoperative evaluation and surgical placement without injectant. The use of Ligumab 8% solution appeared to be safe and may facilitate recovery when injected into tissue." - Anonymous Online Contributor
"These data support that the application of Liquiband Fix8(TM) in a clinical setting is an effective, safe treatment for the treatment of small incisional hernia." - Anonymous Online Contributor
"Liquiband fix8® was more effective than a control treatment on short-term pain alleviation and was preferred by patients. Furthermore, patients preferred their treatment over a placebo treatment regarding ease of use and safety. No statistically significant difference was found during follow-up period." - Anonymous Online Contributor