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Immunosuppressant

All participants for Dry Eye Syndrome

N/A

Recruiting

Research Sponsored by University of Waterloo

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up within 10 minutes of drop instillation

Awards & highlights

Study Summary

This trial is testing if cooling eye drops with cyclosporine A can reduce the burning and stinging when applied to the eyes of those with dry eye disease.

Who is the study for?

This trial is for adults over 18 with dry eye disease, evidenced by specific scores on the Ocular Surface Disease Index and Strip meniscometry tests. It's not suitable for contact lens wearers, pregnant or breastfeeding individuals, those allergic to fluorescein, or patients with certain ocular conditions or taking medications that could affect the study.Check my eligibility

What is being tested?

The study examines whether refrigerating Cequa (0.09% cyclosporine A ophthalmic solution) makes it more comfortable to use for treating dry eye syndrome. The discomfort of burning and stinging upon application is a common issue being addressed.See study design

What are the potential side effects?

Patients using Cequa have reported discomfort such as burning and stinging sensations when applying the drops. These side effects may discourage continued use necessary for managing dry eye disease.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ within 10 minutes of drop instillation

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~within 10 minutes of drop instillation

This trial's timeline: 3 weeks for screening, Varies for treatment, and within 10 minutes of drop instillation for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Ocular discomfort score. A subjective questionnaire that queries participants' ocular discomfort. The instrument ranges from 0 (no discomfort) to 10 (maximum discomfort).

Trial Design

1Treatment groups

Experimental Treatment

Group I: All participantsExperimental Treatment1 Intervention

All participants will have a refrigerated 0.09% cyclosporine drop instilled in one eye, and a non-refrigerated 0.09% cyclosporine drop instilled in the other eye. The eye that receives the refrigerated drop is randomly determined.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of WaterlooLead Sponsor

124 Previous Clinical Trials

209,318 Total Patients Enrolled

Sun Pharmaceutical Industries LimitedIndustry Sponsor

64 Previous Clinical Trials

13,471 Total Patients Enrolled

Media Library

0.09% cyclosporine A ophthalmic solution (Immunosuppressant) Clinical Trial Eligibility Overview. Trial Name: NCT05957211 — N/A

Dry Eye Syndrome Research Study Groups: All participants

Dry Eye Syndrome Clinical Trial 2023: 0.09% cyclosporine A ophthalmic solution Highlights & Side Effects. Trial Name: NCT05957211 — N/A

0.09% cyclosporine A ophthalmic solution (Immunosuppressant) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05957211 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research project presently accepting participants?

"Affirmative. The clinicaltrials.gov website attests to the fact that this trial is currently accepting applicants, having been initially posted on May 19th 2023 and most recently edited on July 13th of the same year. 40 participants are needed from a single medical centre for participation in this study."

Answered by AI

What is the enrollment number for this medical experiment?

"Indeed, according to clinicaltrials.gov, this trial is currently open for enrollment. Initially posted on May 19th 2023 and most recently updated on July 13th 2023, the study seeks 40 participants from a single site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Improving Drop Instillation Comfort of a Cyclosporine A Solution

2023. "Improving Drop Instillation Comfort of a Cyclosporine A Solution". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05957211.

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