Your session is about to expire
← Back to Search
Participants with no obstruction of the lacrimal system for Lacrimal Duct Obstruction
Study Summary
Purpose: It is unknown whether instillation of a drop of anesthetic ophthalmic solution into the eye such as proparacaine hydrochloride 0.5% prior to probing and irrigation of the tear duct (lacrimal drainage) system improves participant comfort during the procedure. To date, there have been no formal studies evaluating the possible benefit of this pretreatment. Methods: Participants 18 years and older who present to the Louisiana State University or associated outpatient ophthalmology clinic(s) with a complaint of epiphora (excessive tearing) who necessitate bilateral lower lid probing and irrigation of the lacrimal drainage system will be enrolled in the study. One eye will be randomized to receive a drop of the anesthetic Proparacaine hydrochloride 0.5% and the other eye will receive a control drop of Balanced Salt Solution (BSS). Probing and irrigation will then be performed in the usual fashion. The participant will then be questioned via survey on a pain scale of 1-5 as to the amount of subjective pain experienced on each side during the procedure. Expected Results: Investigators expect participants will experience statistically significantly less pain in eyes that have received a drop of Proparacaine hydrochloride 0.5% prior to performance of probing and irrigation compared to the eyes which have received the control drop.
- Lacrimal Duct Obstruction
- Dacryocystitis
- Watery Eyes
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
Find a Location
Who is running the clinical trial?
Frequently Asked Questions
What risks may arise when someone has an unobstructed lacrimal system?
"Clinical evidence suggests that the treatment being studied is safe for those with unobstructed tear ducts, resulting in a score of 3."
Is this experiment currently accessible to volunteers?
"As detailed on clinicaltrials.gov, this research project is presently recruiting participants. This trial has been available since June 30th 2020 and was recently updated on December 15th 2022."
What is the current cap for participants in this clinical experiment?
"Affirmative, the information located on clinicaltrials.gov offers evidence that this trial is actively seeking participants. This study was first posted on June 30th 2020 and recently updated December 15th 2022; with a goal of enrolling 145 persons across 1 medical centre."
Share this study with friends
Copy Link
Messenger