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Behavioral Activation Therapy for Depression
Study Summary
This trial will compare brain activation of depressed adolescents before, during, and after a course of Behavioral Activation therapy, using functional magnetic resonance imaging. The goal is to see if BA therapy affects different neural mechanisms for behavioral avoidance associated with low motivation, as compared to threat avoidance.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2022 Phase 4 trial • 494 Patients • NCT03688100Trial Design
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Who is running the clinical trial?
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- I am currently taking medication for my mental health.I have been diagnosed with major depressive disorder.I can receive care without staying in the hospital.My ADHD medication was changed less than a month ago.I am between 15 and 17 years old.I haven't taken any mental health medications, except for ADHD treatment, recently.I have a neurological disorder or epilepsy.I have been diagnosed with a developmental, conduct disorder, severe anorexia, OCD, or autism.I have had a severe head injury or was unconscious for over 30 minutes.
- Group 1: MDD patients
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
For whom is this clinical trial best suited?
"This clinical study is enrolling 136 adolescents between 15-17 years of age who suffer from depression. To be eligible, male and female candidates must present a CDRS-R raw score above 45 (T-score > 65), possess an estimated full scale IQ higher than 80, abstain from other psychosocial treatments as well as psychotropic medications in the two weeks prior to consent with the exception of those prescribed for ADHD management. Additionally, participants should have access to digital platforms like smartphones or tablets that allow them to complete their EMA portion of the trial. As for healthy controls, they cannot meet criteria for MDD and their CD"
Are enrollees being accepted for this experiment at the present time?
"As per clinicaltrials.gov, this medical study is not taking on participants at the moment - it was first published November 1st 2022 and recently modified October 11th 2022. However, 1133 other studies are currently recruiting patients."
Can persons less than seventy years of age partake in this trial?
"This experiment is open to adolescents between the ages of 15 and 17."
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