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Cognitive Bias Modification for Obsessive-Compulsive Disorder
N/A
Recruiting
Research Sponsored by Mclean Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up weeks 0, 1, 2, 3, and 4
Awards & highlights
Study Summary
This trial will examine if CBM-I or AAT is an effective addition to treatment as usual for OCD and related disorders.
Who is the study for?
This trial is for adults with OCD or related disorders currently receiving treatment at the McLean Hospital OCD Institute. Participants must consent to the main study protocol and meet specific criteria, like scoring high on certain scales that measure obsessive beliefs and contamination fears.Check my eligibility
What is being tested?
The study tests Cognitive Bias Modification for Interpretation (CBM-I) and Approach Avoidance Training (AAT), which are computerized tasks aimed at changing negative thought patterns and reactions to feared stimuli in people with OCD. It compares these methods against psychoeducation and a sham training.See study design
What are the potential side effects?
Since CBM-I, AAT, psychoeducation, and sham training are non-invasive psychological interventions primarily involving computer tasks, they typically do not have physical side effects. However, participants may experience temporary increases in anxiety or discomfort.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ weeks 0, 1, 2, 3, and 4
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~weeks 0, 1, 2, 3, and 4
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change in Average Score on Obsessive Beliefs Questionnaire
Secondary outcome measures
Change in Average Score on Behavioral Inhibition/Behavioral Activation Scales
Change in Average Score on Depressive Symptom Index Suicidality Subscale. There are 4 items scored from 0-3 with greater numbers indicating greater severity.
Change in Average Score on Yale-Brown Obsessive Compulsive Scale
+6 moreTrial Design
4Treatment groups
Experimental Treatment
Placebo Group
Group I: Cognitive bias modification with treatment as usualExperimental Treatment1 Intervention
Participants in this group will receive usual treatment in the program and 8 sessions of a computerized cognitive training targeting interpretation bias
Group II: Approach avoidance training with treatment as usualExperimental Treatment1 Intervention
Participants in this group will receive usual treatment in the program and 8 sessions of a computerized cognitive training targeting automatic approach tendencies
Group III: Psychoeducation with treatment as usualPlacebo Group1 Intervention
Participants in this group will receive usual treatment in the program and 8 sessions of psychoeducation
Group IV: Inactive sham approach avoidance trainingPlacebo Group1 Intervention
Participants in this group will receive usual treatment in the program and 8 sessions of a sham approach avoidance training
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Who is running the clinical trial?
Mclean HospitalLead Sponsor
213 Previous Clinical Trials
21,594 Total Patients Enrolled
9 Trials studying Obsessive-Compulsive Disorder
643 Patients Enrolled for Obsessive-Compulsive Disorder
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Eligibility Criteria:
This trial includes the following eligibility criteria:- I can use a computer for 20 minutes without a break.You have had a serious head injury in the past.I was diagnosed with a psychotic disorder when I was admitted.I am currently experiencing symptoms of severe mood swings or hallucinations.I am currently receiving ECT treatment.
Research Study Groups:
This trial has the following groups:- Group 1: Psychoeducation with treatment as usual
- Group 2: Cognitive bias modification with treatment as usual
- Group 3: Inactive sham approach avoidance training
- Group 4: Approach avoidance training with treatment as usual
Awards:
This trial has 0 awards, including:Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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