Experimental: Investigate the effects of an exercise intervention on retired APF players for Acute Pain

Phase-Based Estimates
1
Effectiveness
1
Safety
University of Illinois at Chicago, Chicago, IL
Acute Pain+5 More
Experimental: Investigate the effects of an exercise intervention on retired APF players - Behavioral
Eligibility
18+
Male
Eligible conditions
Acute Pain

Study Summary

This study is evaluating whether an exercise intervention may help improve health and function for retired professional football players.

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Eligible Conditions

  • Acute Pain
  • Depression
  • Chronic Pain
  • Brain Injuries
  • Wounds
  • Chronic Pain Due to Injury
  • Wounds and Injuries

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Experimental: Investigate the effects of an exercise intervention on retired APF players will improve 1 primary outcome and 3 secondary outcomes in patients with Acute Pain. Measurement will happen over the course of 18 months.

18 Months
Rate at which participants will display alterations in brain wave function
18 months
Rate at which exercise will positively affect body composition
Rate at which participants will have overall improved sense of well-being, increased independence, quality of life, and decreased depression
Rate at which participants will see improvements in their physical abilities

Trial Safety

Safety Estimate

1 of 3

Trial Design

2 Treatment Groups

Control
Investigate the effects of an exercise intervention on retired APF players

This trial requires 20 total participants across 2 different treatment groups

This trial involves 2 different treatments. Experimental: Investigate The Effects Of An Exercise Intervention On Retired APF Players is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Investigate the effects of an exercise intervention on retired APF players
Behavioral
20 retired APF players (≥ 18 years of age), who suffer from chronic pain, will be enrolled.
ControlNo treatment in the control group

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 18 months
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 18 months for reporting.

Who is running the study

Principal Investigator
E. B.
Prof. Enrico Benedetti, Warren H. Cole Chair in Surgery, Professor and Head of Surgery, Medical Director, Abdominal Organ Transplant Program
University of Illinois at Chicago

Closest Location

University of Illinois at Chicago - Chicago, IL

Eligibility Criteria

This trial is for male patients aged 18 and older. There are 2 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
A player who has retired from the APF and who has no minimum duration or career length requirement. show original
In order to vote in an election in the United States, you must be 18 years of age or older. show original

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the signs of acute pain?

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A variety of physical, behavioural and emotional signs can be seen in pain. These signs can vary in terms of: duration and severity of the pain, person's past medical knowledge, personality type and coping styles. Some doctors may consider pain signs 'normal', or consider it 'not possible' to differentiate an underlying physical cause for the pain, before the underlying cause is identified. This leads to a delay in treatment. It is important for the doctor and patient to work together in determining the most effective and reasonable referral for appropriate treatment.

Unverified Answer

What are common treatments for acute pain?

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Many acute pain patients receive either opioid, opioid, non-opioid or both, according to their diagnosis. A minority of acute pain patients receive nonsteroidal antiinflammatory drugs, antipsoricidal medication and corticosteroids.

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Can acute pain be cured?

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Data from a recent study suggests that pain is not always a mere symptom, and that chronic pain, being a different entity, is a common and disabling symptom in a large number of patients suffering from a variety of pathologies and may also be a manifestation of chronic pain.

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How many people get acute pain a year in the United States?

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By 2015, pain is expected to become the third most prevalent reason for ED visits in the U.S. Almost 1 in 5 patients in the U.S. will visit the ED to have their pain treated. We need to devise and evaluate strategies to better meet these high standards for pain care.

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What is acute pain?

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Acute pain is pain that comes about as part of normal tissue repair after an injury or surgery. The most common symptoms include a burning or aching pain and an associated feeling of tingling. While acute surgical pain can feel like a very severe form of chronic pain, it occurs due to surgical or surgical-related damage to the nerve tissue.\n

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What causes acute pain?

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Pain exists within the body because neurons communicate pain information in the brain. The brain calculates what's wrong with an injured or damaged body part and sends impulses along the spinal cord and peripheral nervous system in an unpleasant way. The first step in the process is perceiving a stimulus and interpreting pain signals.

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Does acute pain run in families?

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Results from a recent paper are in agreement with the concept that pain perception is influenced by individual factors, but suggests that this is also influenced by genetic predisposition. There is little evidence at present, however, that familiality represents a risk factor for chronic pain. Results from a recent paper may be consistent with a gene-environment interaction effect. This could have public health implications as it might suggest that lifestyle modifications or medical treatment and rehabilitation may be more effective in preventing pain in certain populations.

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How serious can acute pain be?

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Because of its potentially destructive consequences, acute abdominal pain must be carefully and promptly evaluated. In the emergency department, [pain severity classification] should be used when possible, since this can lead to faster management.

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How does experimental: investigate the effects of an exercise intervention on retired apf players work?

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Exercise, specifically high-intensity aerobic training, improved selected measures of health-related fitness in retired Australian rules footballers who report significant disability. Furthermore, the intervention may have beneficial effects on HRQoL domains that are particularly important to these retired individuals. In conclusion, we recommend the concept of the potential value of exercise for improving selected health-related parameters of health for athletes, especially those who are retired.

Unverified Answer

What are the latest developments in experimental: investigate the effects of an exercise intervention on retired apf players for therapeutic use?

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It is concluded that a moderate exercise intervention is effective to reduce pain complaints of apf players affected by chronic musculoskeletal illness which in part is related to physical inactivity. Also fatigue, sleep disturbances, and poor wellbeing are associated with pain in retired athletes.

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Have there been any new discoveries for treating acute pain?

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There are ongoing developments in the science of [pain management](https://www.withpower.com/clinical-trials/pain-management). The use of neuroimaging tools (fMRI, PET) for mapping neural circuitry for pain has progressed in the past 10 to 15 years. An important new development is the use of opioid-based therapies. Although morphine and buprenorphine are effective analgesics that are well tolerated in acute pain settings, more efficient alternatives are now being developed and are showing promising results in chronic pain as well. An example of this development is the use of ketamine or clonidine in acute pain management. These compounds may have a positive impact in acute pain management with very few side-effects.

Unverified Answer

What does experimental: investigate the effects of an exercise intervention on retired apf players usually treat?

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The findings indicate that an exercise intervention can be successfully applied in a group of retired AFL players who usually consult their general practitioner for any musculoskeletal or nonspecific pain complaints. Exercise, however, seems to be of limited effect when compared with other treatments such as acetaminophen or a low dose of nonsteroidal anti-inflammatory drugs.

Unverified Answer
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