Brain Imaging for Concussion in Former NFL Players

"Unfortunately, no further participants are needed for this trial; it was initially posted on March 12th 2020 and the most recent update was November 23rd 2022. However, there are currently 76 different trials recruiting patients with concussion or brain issues and 2 distinct studies for this intervention that still require enrolment."

"The therapeutic intervention was initially investigated in 2018 by Mayo Clinic. At present, two completed studies and two active trials exist; a considerable portion of these are administered out of Chapel Hill, North carolina."

"Admission to this medical trial requires that participants have experienced a concussion, possess healthy brain tissue and fall in between the ages of 50-70. 250 individuals are needed for successful enrolment."

"This clinical trial has a narrow age requirement, seeking out patients between 50 and 70. There are separate studies for those younger than 18 or older than 65 with 26 and 35 trials respectively."

"According to clinical trials.gov, this medical trial is not presently recruiting participants. Initially posted on March 12th 2020 and last updated on November 23rd 2022, the study has yet to accept any patients; however 78 other studies are actively enrolling at this time."

"Our internal evaluation gives this treatment a rating of 1 due to the few data points available in Phase 1 trials that support its efficacy and safety."

"The primary outcome sought by this clinical trial, to be measured at the baseline is Radial Diffusivity (RD) as derived from Tract-Based Diffusion. Secondary outcomes encompass Alcohol Use Disorders Identification Test (AUDIT), National Institute of Health Toolbox Cognitive Battery and Drug Abuse Screening Test-10 (DAST-10). These tests evaluate hazardous alcohol use, dependence symptoms, cognitive functioning and drug abuse over a 3 year followup respectively with scores ranging from 0 - 40 for AUDIT, infinite range for NIHTBXCogBatt and 0 - 10 for DAST-10."