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Colonoscopy Techniques for Inflammatory Bowel Disease

N/A
Waitlist Available
Research Sponsored by Beth Israel Deaconess Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
History of UC or colonic Crohn's disease or unclassified colitis patients with or without colonic adenoma history
Mucosal lesion involves ≥ 1/3 of the colon
Timeline
Screening 3 weeks
Treatment Varies
Follow Up immediately after the procedure
Awards & highlights

Study Summary

This trial is studying whether one colonoscopy technique is better than another for detecting colon cancer in patients with IBD.

Who is the study for?
This trial is for adults over 18 with a history of Ulcerative Colitis, Crohn's disease affecting the colon, or unclassified colitis lasting at least eight years, or any duration if also diagnosed with primary sclerosing cholangitis. Participants must have significant colon involvement and not had a total colectomy or recent colonoscopy.Check my eligibility
What is being tested?
The study compares two techniques to screen for cancer in patients with long-term IBD: High Definition Colonoscopy (HDC) versus Dye Spraying Chromocolonoscopy (DSC), using high-definition cameras to detect abnormal growths in the colon.See study design
What are the potential side effects?
Potential side effects may include discomfort from the procedure, reactions to dye used in DSC such as allergic responses, and risks typically associated with standard colonoscopies like bleeding or perforation.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I have a history of ulcerative colitis, Crohn's disease, or unspecified colitis, with or without a history of colon polyps.
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My colon lesion affects more than one-third of it.
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I was diagnosed over 8 years ago or have primary sclerosing cholangitis.
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I am 18 years old or older.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~immediately after the procedure
This trial's timeline: 3 weeks for screening, Varies for treatment, and immediately after the procedure for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Detection rate of dysplastic lesions in High Definition White Light Colonoscopy versus Dye Spraying Chromo-colonoscopy
Secondary outcome measures
Appropriateness of reported follow up recommendations per standard guideline recommendations
Detection rate of Adenoma in both groups.
Detection rate of high-grade dysplasia in both groups.
+4 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: High Definition White Light ColonoscopyExperimental Treatment1 Intervention
Group II: Dye Spraying Chromo-colonoscopyActive Control1 Intervention

Find a Location

Who is running the clinical trial?

Beth Israel Deaconess Medical CenterLead Sponsor
837 Previous Clinical Trials
13,009,772 Total Patients Enrolled

Media Library

Dye Spraying Chromocolonoscopy Clinical Trial Eligibility Overview. Trial Name: NCT04191655 — N/A
Inflammatory Bowel Disease Research Study Groups: Dye Spraying Chromo-colonoscopy, High Definition White Light Colonoscopy
Inflammatory Bowel Disease Clinical Trial 2023: Dye Spraying Chromocolonoscopy Highlights & Side Effects. Trial Name: NCT04191655 — N/A
Dye Spraying Chromocolonoscopy 2023 Treatment Timeline for Medical Study. Trial Name: NCT04191655 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
High Definition Colonoscopy (HDC) vs. Dye Spraying Chromo-colonoscopy (DSC) in Screening Patients With Long-standing Inflammatory Bowel Disease (IBD)
Joseph Feuerstein 2019. "High Definition Colonoscopy (HDC) vs. Dye Spraying Chromo-colonoscopy (DSC) in Screening Patients With Long-standing Inflammatory Bowel Disease (IBD)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04191655.
All > Inflammatory Bowel Disease > Ibd
~120 spots leftby Dec 2025
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