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Procedure

Variable amplitude for Depression

N/A

Recruiting

Led By Chris Abbott, MD

Research Sponsored by University of New Mexico

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Diagnosis of major depressive disorder or bipolar II

Clinical indications for ECT with right unilateral electrode placement

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 4 weeks

Awards & highlights

Study Summary

This trial will compare two types of electrical therapy for older depressed patients. The goal is to see which type is better for improving mood and cognitive function. The trial will have 50 participants, with

Who is the study for?

This trial is for older adults with major depressive disorder or bipolar II who need ECT treatment. Participants should be suitable for right unilateral electrode placement. It's not specified, but typically those with certain health conditions or incompatible treatments would be excluded.Check my eligibility

What is being tested?

The study is testing if adjusting the electric current (amplitude) during ECT can improve depression and cognitive outcomes compared to a fixed amplitude of 800 mA. Half of the participants will receive individualized amplitude adjustments, while the other half will get the standard fixed level.See study design

What are the potential side effects?

While side effects are not detailed here, common ones associated with ECT include confusion immediately after treatment, memory loss, physical side effects like headaches or muscle aches, and in rare cases more serious complications.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have been diagnosed with major depression or bipolar II.

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I am recommended to undergo ECT with electrodes placed on the right side of my head.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 4 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~4 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Delis Kaplan Executive Function System Letter Fluency

Inventory of Depressive Symptomatology - Clinician Rated

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Variable amplitudeExperimental Treatment1 Intervention

Individualized amplitude

Group II: Fixed amplitudeActive Control1 Intervention

Fixed (800 milliamperes) amplitude

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

National Institute of Mental Health (NIMH)NIH

2,786 Previous Clinical Trials

2,689,717 Total Patients Enrolled

666 Trials studying Depression

251,534 Patients Enrolled for Depression

University of New MexicoLead Sponsor

372 Previous Clinical Trials

3,528,739 Total Patients Enrolled

14 Trials studying Depression

2,822 Patients Enrolled for Depression

Chris Abbott, MDPrincipal InvestigatorUniversity of New Mexico

1 Previous Clinical Trials

62 Total Patients Enrolled

1 Trials studying Depression

62 Patients Enrolled for Depression

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the enrollment for this medical study currently accepting new participants?

"Indeed, based on the details available on clinicaltrials.gov, this trial is actively seeking individuals to participate. The initial posting date for the study was September 14th, 2023, and it underwent its latest revision on December 15th, 2023."

Answered by AI

What is the current number of participants under observation in this clinical investigation?

"Indeed, the details provided on clinicaltrials.gov indicate that this trial is currently in the recruitment phase. The study was initially posted on September 14th, 2023 and underwent its most recent update on December 15th, 2023. A total of 50 patients are sought to participate in this trial at a single site."

Answered by AI