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N-acetylcysteine for COVID-19
Study Summary
This trial is testing whether or not N-acetylcysteine can help fight the COVID-19 virus by boosting a type of cell in your immune system.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I am 18 years old or older.You have tested positive for COVID-19.I need extra oxygen to keep my oxygen levels normal.Patients with certain types of blood cancers may be allowed to join the study after their doctor reviews their blood test results.You need a machine to help you breathe or have to stay in a special hospital unit at MSK.You have been admitted to a specific intensive care unit at MSK or are currently using a machine to help you breathe.Your absolute lymphocyte count is less than 1.0/mm3.
- Group 1: mechanically ventilated &/or managed in a critical-care
- Group 2: non-mechanically ventilated, non-critical-care
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are any fresh participants being sought for the trial?
"The trial data found on clinicaltrials.gov indicates that at the present time, this particular medical investigation is not looking for participants; while it was initially posted in May of 2020 and most recently updated in July 2022, recruitment has now ceased. Nonetheless, there are still 1755 separate research projects actively searching for volunteers to participate."
Are there any additional experiments involving N-acetylcysteine that have been conducted?
"At present, 38 clinical trials are underway for N-acetylcysteine. These can be broken down into 7 Phase 3 trials and many more research locations (44 in total) which primarily reside in New york City."
What therapeutic applications does N-acetylcysteine have?
"N-acetylcysteine is an effective solution for corneal ulceration and can additionally be deployed to abate acute rhinitis, acetaminophen toxicity, as well as a handful of other ocular pathologies."
Has the Food and Drug Administration given its stamp of approval to N-acetylcysteine?
"Our team believes that N-acetylcysteine's safety is rated a 2, as there has been preliminary research done to affirm its security but no trials have established its efficacy."
How many individuals are participating in this scientific trial?
"Unfortunately, enrollment for this medical trial has concluded. First posted on May 1st 2020 and last updated July 22nd 2022, the study is no longer seeking participants. However, should one be interested in similar studies there are 1717 ongoing trials associated with infections and 38 that involve N-acetylcysteine actively recruiting patients."
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