Cimetidine Excretion During Lactation

"This trial has set 18 years as the minimum age for entry and 50 years as the upper limit."

"Eligibility to participate in this medical trial is limited to patients who are lactating and aged between 18-50 years old. The research team has set out to recruit 50 individuals as part of the study."

"According to clinicaltrials.gov, this research project is actively seeking out participants. The listing was first posted on October 1st 2023 and updated for the final time on September 20th of that same year."

"Healthy lactating women are considered safe to use this treatment, so it garnered a score of 3. The approval was given because the Phase 4 trial demonstrated that this medication is suitable for these individuals."

"Affirmative. According to records on clinicaltrials.gov, this medical trial is actively seeking participants as of September 20th, 20203. This research was initially made public on October 1st and requires 50 volunteers across a single site."

"The primary goal of this trial, assessed at 3-5 weeks postpartum, 3-4 months postpartum and 6-8 months postpartum is to examine Mammary Epithelial Cell expression levels of BCRP. Secondary goals include evaluating the Relationship between OCT1 expression and activity (as defined by Effect of time postpartum on OCT1 protein expression in MECs and correlation with cimetidine mammary CL), assessing Maternal Cimetidine PK (or Effects of time postpartum on cimetidine elimination rate constant) as well as examining the Relationship between BCRP expression and activity (defined by"