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Nightmare Reduction Techniques for Narcolepsy

Waitlist Available
Led By Jennifer Mundt, PhD
Research Sponsored by Northwestern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Diagnosis of narcolepsy
Receiving standard medical care for narcolepsy
Screening 3 weeks
Treatment Varies
Follow Up duration of study (11-13 weeks)
Awards & highlights

Study Summary

This trial will test two treatments to reduce nightmares in narcolepsy patients. Participants will log sleep symptoms & complete questionnaires & a sleep study.

Who is the study for?
Adults with narcolepsy who often have nightmares (at least 3 times a week) can join this study. They must be stable on sleep and psychiatric meds for 3 months, speak English, live in the US, and be able to visit Evanston, IL for appointments. Those already in psychotherapy or with previous nightmare treatments cannot participate.Check my eligibility
What is being tested?
The trial is testing if imagery rehearsal therapy (IRT) helps reduce nightmares in people with narcolepsy and if adding targeted dream control (TDC) improves results. Participants will track their sleep, attend treatment sessions, fill out questionnaires, and some will do a sleep study nap.See study design
What are the potential side effects?
Since the interventions are behavioral therapies like IRT and TDC rather than medications, they may not have typical side effects but could include temporary increases in nightmare frequency or distress due to focusing on dreams during treatment.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
You have been diagnosed with narcolepsy.
You are currently receiving regular medical treatment for narcolepsy.
You have nightmares at least three times a week.
You have been taking the same sleep and psychiatric medications for at least 3 months.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~duration of study (11-13 weeks)
This trial's timeline: 3 weeks for screening, Varies for treatment, and duration of study (11-13 weeks) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Daily diary

Trial Design

2Treatment groups
Experimental Treatment
Group I: Imagery rehearsal therapy and targeted dream control (IRT+TDC)Experimental Treatment2 Interventions
Participants randomized to this group will receive 7 sessions of IRT+TDC.
Group II: Imagery rehearsal therapy (IRT)Experimental Treatment1 Intervention
Participants randomized to this group will receive 7 sessions of IRT.

Find a Location

Who is running the clinical trial?

Northwestern UniversityLead Sponsor
1,580 Previous Clinical Trials
916,853 Total Patients Enrolled
2 Trials studying Narcolepsy
95 Patients Enrolled for Narcolepsy
Jennifer Mundt, PhDPrincipal InvestigatorNorthwestern University
1 Previous Clinical Trials
60 Total Patients Enrolled
1 Trials studying Narcolepsy
60 Patients Enrolled for Narcolepsy

Media Library

Imagery rehearsal therapy Clinical Trial Eligibility Overview. Trial Name: NCT05709873 — N/A
Narcolepsy Research Study Groups: Imagery rehearsal therapy (IRT), Imagery rehearsal therapy and targeted dream control (IRT+TDC)
Narcolepsy Clinical Trial 2023: Imagery rehearsal therapy Highlights & Side Effects. Trial Name: NCT05709873 — N/A
Imagery rehearsal therapy 2023 Treatment Timeline for Medical Study. Trial Name: NCT05709873 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any remaining slots for participants in this experiment?

"The details hosted on clinicaltrials.gov indicate that this particular trial is not currently recruiting participants; it was first posted in March 1st 2023 and last updated January 24th, 2023. Nevertheless, there are 12 other medical studies seeking enrollees of the moment."

Answered by AI

Who else is applying?

What site did they apply to?
Northwestern University
What portion of applicants met pre-screening criteria?
Met criteria

Why did patients apply to this trial?

Narcolepsy impacts my life a lot and I'd like there to be better treatments.
PatientReceived 2+ prior treatments
~0 spots leftby May 2024