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Radiation Therapy

Cohort A for Brain Tumor

N/A

Waitlist Available

Led By Kevin R. Shiue, MD

Research Sponsored by Indiana University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 year

Awards & highlights

Study Summary

This trial is designed to test two de-escalated whole brain radiation therapy (WBRT) dose levels and assess their ability to maintain acceptable in-brain distant control.

Eligible Conditions

Metastatic Brain Tumors

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

In-brain distant failure rate

Secondary outcome measures

Change in health-related quality of life

Change in neurocognitive function

Change in performance status

+3 more

Trial Design

2Treatment groups

Experimental Treatment

Group I: Cohort BExperimental Treatment1 Intervention

Low PCI dose

Group II: Cohort AExperimental Treatment1 Intervention

Standard PCI dose

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Cohort A

2020

Completed Phase 2

~120

Cohort B

2020

Completed Phase 1

~90

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Find a Location

Who is running the clinical trial?

Indiana UniversityLead Sponsor

980 Previous Clinical Trials

983,141 Total Patients Enrolled

Kevin R. Shiue, MDPrincipal InvestigatorIndiana University School of Medicine

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the utmost number of individuals participating in this exploration?

"Affirmative. Clinicaltrials.gov displays that this medical trial, which debuted on July 6th 2017, is still recruiting participants. 40 people have to be enrolled from 3 separate clinical sites."

Answered by AI

Are there presently any vacancies for this therapeutic trial?

"According to the clinicaltrials.gov database, this medical experiment is actively accepting participants and was initially published on July 6th 2017 before being updated most recently on September 20th 2022."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Pilot Phase 2 Study Whole Brain Radiation Therapy With Simultaneous Integrated Boost for Patients With Brain Metastases

Kevin Shiue, MD 2017. "Pilot Phase 2 Study Whole Brain Radiation Therapy With Simultaneous Integrated Boost for Patients With Brain Metastases". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03189381.