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Exercise for Atrial Fibrillation (ACUTE-AF Trial)

N/A
Recruiting
Led By Jennifer Reed, PhD
Research Sponsored by Ottawa Heart Institute Research Corporation
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
If female, self-reports being post-menopausal
At least 40 years of age
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion, an average of 1.5 years
Awards & highlights
No Placebo-Only Group

ACUTE-AF Trial Summary

This trial will test whether exercise can help relieve symptoms in people with atrial fibrillation.

Who is the study for?
This trial is for men and women over 40 with symptomatic atrial fibrillation (AF) who can exercise safely. Participants must have had AF symptoms recently, women should be post-menopausal, and all must understand English or French. Excluded are those already exercising regularly, with unstable heart conditions or severe diabetes, unable to use a smartphone or the internet, or with certain cardiac devices.Check my eligibility
What is being tested?
The study tests how different types of exercise affect short-term changes in AF symptoms. It compares moderate-intensity continuous training (MICT), high-intensity interval training (HIIT), and no vigorous exercise over one week in a randomized crossover design where participants will try each condition.See study design
What are the potential side effects?
While specific side effects aren't listed for this type of physical activity intervention, general risks may include muscle soreness, fatigue, and potential exacerbation of AF symptoms during or after exercise.

ACUTE-AF Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am a woman and have gone through menopause.
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I am 40 years old or older.
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I have irregular heartbeats that come and go or persist.
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I have felt symptoms in the last 4 weeks.

ACUTE-AF Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion, an average of 1.5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, an average of 1.5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Feasibility of the pilot study - Adverse events
Feasibility of the pilot study - Participant fidelity
Feasibility of the pilot study - Recruitment and consent rate
+2 more
Secondary outcome measures
AF status measured daily with a KardiaMobile device
AF symptoms self-reported with a 7-day patient symptom questionnaire

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

ACUTE-AF Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Moderate Intensity Continuous Training (MICT)Experimental Treatment1 Intervention
Participants will do 3 sessions of moderate-intensity continous exercise training over 7 days
Group II: High Intensity Interval Training (HIIT)Experimental Treatment1 Intervention
Participants will do 3 sessions of high-intensity interval training over 7 days
Group III: RestActive Control1 Intervention
Participants will abstain from doing moderate- to high-intensity interval training over 7 days
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
High-intensity interval training (HIIT)
2016
N/A
~270

Find a Location

Who is running the clinical trial?

Ottawa Heart Institute Research CorporationLead Sponsor
187 Previous Clinical Trials
92,346 Total Patients Enrolled
23 Trials studying Atrial Fibrillation
6,655 Patients Enrolled for Atrial Fibrillation
Jennifer Reed, PhDPrincipal InvestigatorOttawa Heart Institute Research Corporation
4 Previous Clinical Trials
246 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research study currently accepting participants?

"Affirmative. Clinicaltrials.gov has information that confirms this clinical trial is seeking enrolment from potential participants, having been posted on February 8th 2022 and edited lastly on November 29th 2022. The study necessitates 36 patients to be recruited at one medical centre."

Answered by AI

What is the aggregate figure of people engaging in this experiment?

"Affirmative. The clinicaltrials.gov website provides evidence that, as of November 29th 2022, this study is still actively seeking applicants. Since its post on February 8th 2022 it has been looking for 36 participants at just one medical centre."

Answered by AI
~1 spots leftby Apr 2024