Treatment for Opioid Use Disorder

Phase-Based Progress Estimates
3
Effectiveness
3
Safety
Opioid Use Disorder
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial is investigating whether it is better to continue taking a low dose of buprenorphine or to discontinue it entirely before surgery, in order to manage postoperative pain without interrupting treatment for opioid use disorder.

Eligible Conditions
  • Opioid Use Disorder

Treatment Effectiveness

Effectiveness Progress

3 of 3
This is further along than 93% of similar trials

Similar Trials

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Remifentanil
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Methadone
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AZD4041 and morphine

Study Objectives

3 Primary · 6 Secondary · Reporting Duration: 48 hours after surgery

24 hours after surgery
Post-operative pain scores: 24 hours after surgery
3 days post-op
Opioid consumption
30 days following surgery
Opioid Cravings
Opioid Misuse
Opioid Relapse
Opioid Withdrawal
Opioid dispensing
48 hours after surgery
Post-operative pain scores: 48 hours after surgery
72 hours after surgery
Post-operative pain scores: 72 hours after surgery

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Similar Trials

1
Remifentanil
1
Methadone
1
AZD4041 and morphine

Trial Design

0 Treatment Group

80 Total Participants · 0 Treatment Group

Primary Treatment: Treatment · No Placebo Group · Phase 4

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 48 hours after surgery

Who is running the clinical trial?

Aurora QuayeLead Sponsor
MaineHealthOTHER
64 Previous Clinical Trials
38,596 Total Patients Enrolled
Aurora Quaye, MDPrincipal InvestigatorMaine Medical Center; Spectrum Healthcare Partners
1 Previous Clinical Trials
76 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 4 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are scheduled for surgery at Maine Medical Center.
References

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