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Selective Serotonin Reuptake Inhibitor (SSRI)

A for Obsessive-Compulsive Disorder

Phase 4
Waitlist Available
Led By John H Greist, MD
Research Sponsored by Rogers Center for Research & Training, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Men and women aged 18 years, with OCD of at least 1 year's duration, meeting DSM-IV diagnostic criteria, and having a baseline Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) score of 18.
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up screening, baseline, and end of weeks 4, 8, 12, 16, 20 and 24.
Awards & highlights

Study Summary

This study will test the hypotheses that: 1. 12 weeks of Luvox-CR plus web-based Cognitive-Behavioral Therapy (CBT) [CT-STEPS] will produce greater symptom relief of OCD than treatment with Luvox-CR alone; and, 2. subjects receiving 12 weeks of CT-STEPS added to Luvox-CR treatment after 12-weeks of Luvox-CR monotherapy will experience greater OCD symptom relief (from weeks 12-24) than those continuing Luvox-CR treatment and having access to CT-STEPS from week one. 3. subjects who begin CT-STEPS at week 12 will be more likely to complete it than those who begin CT-STEPS at baseline.

Eligible Conditions
  • Obsessive-Compulsive Disorder

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~screening, baseline, and end of weeks 4, 8, 12, 16, 20 and 24.
This trial's timeline: 3 weeks for screening, Varies for treatment, and screening, baseline, and end of weeks 4, 8, 12, 16, 20 and 24. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
The measure (Y-BOCS score) will be obtained by clinician rating

Trial Design

1Treatment groups
Experimental Treatment
Group I: AExperimental Treatment2 Interventions
Effectiveness of Luvox CR plus Web-based CBT for OCD
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Behavioral Therapy
2003
Completed Phase 4
~1210

Find a Location

Who is running the clinical trial?

Rogers Center for Research & Training, Inc.Lead Sponsor
1 Previous Clinical Trials
20 Total Patients Enrolled
John H Greist, MDPrincipal InvestigatorThe Rogers Center for Research & Training, Inc.
1 Previous Clinical Trials
20 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Cost-Effectiveness of Adding Web-Based Cognitive-Behavioral Therapy (CBT) to Luvox CR for Obsessive Compulsive Disorder (OCD)
2008. "Cost-Effectiveness of Adding Web-Based Cognitive-Behavioral Therapy (CBT) to Luvox CR for Obsessive Compulsive Disorder (OCD)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00743834.
All > Obsessive Compulsive Disorder > Ocd
~3 spots leftby May 2025
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