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Anti-metabolites

Short Course Radiation for Pancreatic Cancer

Phase 2
Waitlist Available
Led By Theodore S Hong, M.D.
Research Sponsored by Massachusetts General Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights

Study Summary

This trial is testing whether proton beam radiation therapy, in combination with two chemotherapy drugs, is effective in controlling the growth of cancer.

Eligible Conditions
  • Pancreatic Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Rate of R0 Resection
Secondary outcome measures
30 Day Post-operative Mortality Rate
Correlation of Mutational Analysis Biomarkers
Local Control Rates
+7 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Treatment ArmExperimental Treatment4 Interventions
All participants will receive the FOLFIRINOX regimen, followed by capecitabine and short course radiation therapy.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Capecitabine
FDA approved
Irinotecan
FDA approved
Surgery
2000
Completed Phase 3
~2550

Find a Location

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor
2,928 Previous Clinical Trials
13,198,307 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,654 Previous Clinical Trials
40,933,105 Total Patients Enrolled
Theodore S Hong, M.D.Principal InvestigatorMassachusetts General Hospital

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
FOLFIRINOX + RT for Pancreatic Cancer
Theodore Sunki Hong 2012. "FOLFIRINOX + RT for Pancreatic Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01591733.
~4 spots leftby Apr 2025
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