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Portable air cleaner (PAC) for Cardiovascular Disease

N/A
Waitlist Available
Led By Jonathan D Newman
Research Sponsored by NYU Langone Health
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Able to measure home blood pressure twice daily
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, week 4
Awards & highlights

Study Summary

This trial is investigating whether reducing air pollution at home can decrease inflammation biomarkers. 74 adults with hypertension will use portable air cleaners at home for 4 weeks and researchers will measure biomarker concentrations before and after.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You can check your blood pressure at home twice a day.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, week 4
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, week 4 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in circulating concentration of Tumor Necrosis Factor alpha (TNFα)
Secondary outcome measures
Change in indoor Particulate Matter < 2.5 um in Diameter (PM2.5) concentration

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Portable Air Cleaner (PAC) groupExperimental Treatment1 Intervention
This study will utilize a portable air cleaner as an intervention for the potential reduction of air pollution-associated inflammation. This commercially available device has no significant risks. The researchers plan to use a commercially available PAC with a "true HEPA" filter for the true arm.
Group II: Sham Portable Air Cleaner (PAC) groupPlacebo Group1 Intervention
For the sham arm, the same model will be used with HEPA filter removed, and has identical appearance and sound. The researchers will use a PAC designed to filter air in rooms up to approximately 350 ft2, with minimal noise on the lowest setting.

Find a Location

Who is running the clinical trial?

NYU Langone HealthLead Sponsor
1,358 Previous Clinical Trials
816,765 Total Patients Enrolled
Jonathan D NewmanPrincipal InvestigatorNYU Langone Health

Media Library

Portable air cleaner (PAC) Clinical Trial Eligibility Overview. Trial Name: NCT05379400 — N/A
Cardiovascular Disease Research Study Groups: Portable Air Cleaner (PAC) group, Sham Portable Air Cleaner (PAC) group
Cardiovascular Disease Clinical Trial 2023: Portable air cleaner (PAC) Highlights & Side Effects. Trial Name: NCT05379400 — N/A
Portable air cleaner (PAC) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05379400 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this experiment accepting new participants at this time?

"Per clinicaltrials.gov, this research trial is no longer enrolling patients; the post originally went live on August 11th 2022 and was recently updated November 22nd of that year. Fortunately, there are still 415 other medical studies actively seeking participants at present."

Answered by AI

Is there an age restriction on participating in this experiment?

"To be a part of this medical study, patients must fall between the ages of 18 to 100. For minors and elderly individuals there are respectively 27 and 369 clinical trials available for their age groups."

Answered by AI

Who is a viable candidate for participating in this investigation?

"This clinical trial is seeking 74 individuals, aged 18 to 100 and suffering from cardiovascular disease. To participate, patients must be non-smokers (excluding e-cigarettes), have a grasp of English or Spanish, understand the study procedures and give their informed consent; they must also have stable hypertension with systolic blood pressure lower than 160 mm Hg (or 130 mm Hg without antihypertensive medications) and be able to measure it twice daily at home. It's necessary for them to attend clinic visits before and after the study period as well as join video conferences in order to get set up at home. Furthermore, participants should"

Answered by AI
~19 spots leftby Mar 2025