Social Network for HIV Infections

1
Effectiveness
1
Safety
AIDS TaskForce of Greater Cleveland, Cleveland, OH
HIV Infections+2 More
Social Network - Behavioral
Eligibility
Any Age
Male
Eligible conditions
HIV Infections

Study Summary

This study is evaluating whether a social network approach can help encourage African-American men who have sex with men to adopt pre-exposure prophylaxis to prevent HIV infection.

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Eligible Conditions

  • HIV Infections
  • Acquired Immunodeficiency Syndrome
  • Human Immunodeficiency Virus (HIV) Infections

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Compared to trials

Study Objectives

This trial is evaluating whether Social Network will improve 1 primary outcome and 5 secondary outcomes in patients with HIV Infections. Measurement will happen over the course of 6 and 15 months.

6 and 15 months
Pre-Exposure Prophylaxis (PrEP) Knowledge
Pre-Exposure Prophylaxis Attitudes
Pre-Exposure Prophylaxis Intentions
Pre-Exposure Prophylaxis Norm Perceptions
Pre-Exposure Prophylaxis Self-Efficacy
Self-report of pre-exposure prophylaxis (PrEP) use

Trial Safety

Safety Estimate

1 of 3

Compared to trials

Trial Design

2 Treatment Groups

Comparison
Social Network Approach

This trial requires 500 total participants across 2 different treatment groups

This trial involves 2 different treatments. Social Network is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Social Network ApproachParticipants will receive brief HIV counseling at baseline visit. Leaders of social networks will be determined using data from participants. These leaders will then be invited to attend a 5-session small-group training that will teach them how to communicate the benefits of PrEP to their social network members. All social network members will be asked about intervention exposure at 6- and 15-month followups.
Comparison
Behavioral
Participants will receive brief HIV counseling at baseline visit.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Social Network
2015
N/A
~5400

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 6 and 15 months
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 6 and 15 months for reporting.

Who is running the study

Principal Investigator
J. K.
Prof. Jeffrey Kelly, Professor
Medical College of Wisconsin

Closest Location

AIDS TaskForce of Greater Cleveland - Cleveland, OH

Eligibility Criteria

This trial is for male patients of any age. There are 8 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Sex with at least one male partner in the past 12 months
Age 16 or older
For the seed only, self-report of HIV-negative serostatus or unknown serostatus
Except for the seed, being named as a friend by an already-enrolled participant
Male at birth
NETWORKS
More than 49% of the seed's eligible friends agree to participate
More than 49% of all network members self-report they are HIV-negative at baseline

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are common treatments for hiv infections?

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The vast majority of hiv infections are successfully treated. Treatment options often coincide with or even depend on the type of hiv infection. They include antiretroviral therapy, chemotherapy, or combinations of both. These treatments can be effective and safe.

Unverified Answer

What causes hiv infections?

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What causes HIV infections? HIV can be transmitted from mother to offspring if her own immune system cannot keep her infection from spreading to her unborn child in the womb, if her own immune system is defective or if she exchanges blood through unsafe sexual practice. Other methods of HIV transmission include breast feeding, rape, sexual or intravenous drug use, and tattooing of the skin, all of which are common among injecting drug injectors in the U.S. In any case, a virus is the reason an individual becomes infected with HIV. The virus attaches to immune cells and enters these cells. It alters them so that they attack those infected cells, preventing CD4+ T-lymphocytes from protecting other organs from the AIDS virus.

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How many people get hiv infections a year in the United States?

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Around 250,000 new cases of HIV are diagnosed each year in the United States. answer: The prevalence of HIV among the adult homosexual community is higher in New York City than other parts of the United States. In New York City, a significant part of the AIDS epidemic was related to intravenous drug use by heterosexuals. The epidemic among the heterosexual population of the United States, however, remains suboptimal.

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Can hiv infections be cured?

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Although the general public's belief in its 'cure', HIV/AIDS, continues to be strong, the disease has no cure and current treatment provides effective control of symptoms.

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What are the signs of hiv infections?

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HIV patients with detectable plasma HIV RNA levels generally present with fever, malaise, swollen lymph nodes and/or symptoms suggestive of advanced disease. However, a history of genital ulceration or an ulcer in a site suggestive of recurrent vulvovaginal herpes simplex infection can be a sign of a genital source of infection. Thus, in patients for whom the history and clinical signs are not sufficiently clear, or in those in whom genital ulceration is a recent symptom, HIV infection should always be suspected and a thorough genital examination should be performed. However, a negative urethral cytology does not rule out the presence of hiv since urethral HSV shedding can occur without systemic infection.

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What is hiv infections?

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HIV infections, commonly referred to as AIDS are a group of infections that can cause several illnesses as well as a death toll. HIV is an entry factor of infections that are sexually transmitted, including the human immunodeficiency virus (HIV) which causes AIDS. Worldwide HIV infections are more than 25.1 million and the number is growing at present.\n

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What are the common side effects of social network?

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We found the most common side effects of social network included fever, dizziness, and headache. Since these side effects may become worse, and could also lead to life-threatening complications, it is essential for all health professionals to learn the signs and symptoms that accompany the most common side effects so as to immediately treat and avoid further complications. On the side of social network, more attention should be paid to health professionals' skills in assessing the condition and in treatment, such as referral or adjustment of drug dosage, rather than merely providing referrals.

Unverified Answer

What does social network usually treat?

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Participants' perceptions of whether they had been supported by social networks and which support networks were used differed among the treatment groups. Participants were more aware of support network type when offered two choices of support (family and social-health) compared with the group receiving only family support. Patients receiving nonhealth support were more likely to indicate social support, while patients receiving health-related social support were more likely to indicate family support, which is expected when assessing family support. We discuss implications of these findings and avenues for follow-up research and practice in social network support for HIV-infected individuals' health care providers.

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What are the latest developments in social network for therapeutic use?

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Overall, social network therapies as an adjunct to conventional therapy seem to have promising results in terms of alleviating the symptoms of CHB in certain settings especially when combined with conventional therapies. However, further research is needed to enhance the effectiveness of social network therapies for this clinical population.

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Who should consider clinical trials for hiv infections?

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Because HIV clinical trials have unique requirements and goals, trials are not likely to be seen as a cost-effort to participate in. In order to see a [clean study design] for HIV, enrollment criteria should be reviewed on a yearly basis. Additionally, clinical trials and clinical practice guidelines can help physicians decide which patient population(s) to participate in clinical trials by informing them of current clinical guidelines. To help clinical trials, clinicians can participate directly in clinical trials. [withpower(https://www.withpower.com/clinical-trials/clinical-practices_guidelines) can help medical professionals find one near you.

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What is the primary cause of hiv infections?

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The high levels of sexual activity may explain the frequent spread. However, sexual intercourse itself has not been shown to be a high-risk event. Sexual and other behavioral factors have no significant effect on the epidemiologic data for any sex.

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How does social network work?

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HIV-positive women with more friends report less anxiety and negative mood, less stress, and higher self-esteem than more socially disadvantaged women. This effect is explained primarily by the more intense social network and peer support for women among those who were more socially and economically deprived. Findings from a recent study support the hypothesis that social support moderates the effects of psychosocial risks for HIV transmission.

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