~3 spots leftby Apr 2026

The Safety and Efficacy of Psilocybin in Participants With Type 2 Bipolar Disorder (BP-II) Depression.

Recruiting at 2 trial locations
SA
Overseen byScott Aaronson, MD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Phase 2
Waitlist Available
Sponsor: Sheppard Pratt Health System
No Placebo Group
Prior Safety Data
Approved in 2 Jurisdictions

Trial Summary

What is the purpose of this trial?

This trial is testing whether psilocybin, a compound from 'magic mushrooms,' can help improve depression in adults with Bipolar II Disorder. The idea is that psilocybin changes brain chemistry to improve mood. Psilocybin has shown promise as a treatment for major depressive disorder and was recognized by the FDA in 2019.

Research Team

SA

Scott Aaronson, MD

Principal Investigator

Sheppard Pratt Health System

Eligibility Criteria

Inclusion Criteria

You have been diagnosed with depression related to Type 2 Bipolar Disorder (BP-II).

Exclusion Criteria

You have other medical conditions in addition to the one being studied.

Treatment Details

Interventions

  • Psilocybin (Psychedelic)
Participant Groups
1Treatment groups
Experimental Treatment
Group I: PsilocybinExperimental Treatment1 Intervention
25mg of Psilocybin

Find a Clinic Near You

Who Is Running the Clinical Trial?

Sheppard Pratt Health System

Lead Sponsor

Trials
23
Recruited
7,800+

COMPASS Pathways

Industry Sponsor

Trials
15
Recruited
1,400+