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Polyphenol
Resveratrol for Dilated Cardiomyopathy (RES-HF Trial)
Phase 3
Waitlist Available
Led By Shelley Zieroth, MD
Research Sponsored by St. Boniface Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months
Awards & highlights
RES-HF Trial Summary
The purpose of this study is to determine if resveratrol can improve heart function and quality of life. Although, population studies have revealed that a mild to moderate intake of red wine reduces cardiovascular disease risk in humans, clinical studies that evaluate the potential heart benefits of resveratrol in patients with non-ischemic cardiomyopathy have not been previously reported. Accordingly, this research is being done because it will fill this deficiency in the information available in the literature and establish the clinical benefits of resveratrol in patients with this type of heart disease.
Eligible Conditions
- Dilated Cardiomyopathy
RES-HF Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 12 months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Cardiac Function
Quality of life
Secondary outcome measures
Inflammatory Marker Measurements
Nitric Oxide Determination
Oxidative Stress
+1 moreRES-HF Trial Design
2Treatment groups
Active Control
Placebo Group
Group I: ResveratrolActive Control1 Intervention
500 mg (1 capsule BID) of resveratrol for 12 months
Group II: PlaceboPlacebo Group1 Intervention
500 mg (1 capsule BID) of placebo for 12 months.
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Who is running the clinical trial?
St. Boniface HospitalLead Sponsor
51 Previous Clinical Trials
11,569 Total Patients Enrolled
Canadian Centre for Agri-Food Research in Health and MedicineOTHER
1 Previous Clinical Trials
243 Total Patients Enrolled
Agriculture and Agri-Food CanadaOTHER_GOV
33 Previous Clinical Trials
2,265 Total Patients Enrolled
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